Results 31 to 40 of about 29,527 (256)

Passive exposure to cannabidiol oil does not cause microbiome dysbiosis in larval zebrafish

open access: yesCurrent Research in Microbial Sciences, 2021
The use of cannabidiol oil derived products has dramatically increased in popularity and is predicted to grow steadily over the next decade. Given its relative stability, cannabidiol is likely to accumulate in the environment and affect aquatic animals ...
Maracela Talamantes   +3 more
doaj   +1 more source

Analyzing cannabinoid-induced abnormal behavior in a zebrafish model.

open access: yesPLoS ONE, 2020
In this study, we investigated locomotor activity and responses to repeated light and dark stimuli to assess cannabinoid-induced abnormal behavior in zebrafish larvae (Danio rerio), as an alternative to standard rodent models.
Akihiro Hasumi   +2 more
doaj   +1 more source

Oral cannabidiol (CBD) as add-on to paracetamol for painful chronic osteoarthritis of the knee: a randomized, double-blind, placebo-controlled clinical trialResearch in context

open access: yesThe Lancet Regional Health. Europe, 2023
Summary: Background: Painful knee osteoarthritis (KOA) is common, pharmacological treatment, however, is often hampered by limited tolerability. Cannabidiol, which preclinically showed anti-inflammatory, analgesic activity, could supplement established ...
Sibylle Pramhas   +6 more
doaj   +1 more source

Cannabidiol: uso en epilepsias refractarias

open access: yes, 2017
Introducción. Algunos síndromes epilépticos se caracterizan por crisis de difícil control y asocian un retraso en el desarrollo neuropsicomotor, lo que conlleva un deterioro en la calidad de vida del paciente y su familia. Objetivo.
Jimbo Sotomayor, Ruth Elizabeth
core   +1 more source

Pronounced State-Level Disparities in Prescription of Cannabinoids to Medicaid Patients

open access: yesMedical Cannabis and Cannabinoids, 2023
Introduction: Dronabinol is approved in the USA for chemotherapy-induced nausea as well as vomiting and HIV-induced anorexia, while cannabidiol is primarily approved for childhood epileptic disorders Lennox-Gastaut and Dravet syndrome.
Edward Y. Liu   +2 more
doaj   +1 more source

Neuroprotection following cerebral ischemia : the potential therapeutic role for cannabidiol [PDF]

open access: yes, 2022
Cerebral ischemia is a cerebrovascular condition characterized by the lack of blood flow to the brain, resulting in multiple and complex pathophysiological processes including excitotoxicity, inflammation, oxidative stress and apoptosis.
Meyer, Erika
core   +1 more source

Successful use of pure cannabidiol for the treatment of super-refractory status epilepticus

open access: yesEpilepsy and Behavior Case Reports, 2018
We present the case of a child with long-standing, super-refractory status epilepticus (SRSE) who manifested prompt and complete resolution of SRSE upon exposure to pure cannabidiol.
Rajsekar R. Rajaraman   +2 more
doaj   +1 more source

Cannabidiol lacks the vanilloid VR1-mediated vasorespiratory effects of capsaicin and anandamide in anaesthetised rats

open access: yes, 2004
The results of vasorespiratory studies in rats anaesthetised with pentobarbital show that (±) cannabidiol, a cannabinoid that lacks psychotropic actions and is inactive at cannabinoid (CB) receptors, does not affect respiration or blood pressure when ...
Smith, Paula J.W.   +4 more
core   +1 more source

Cannabinoid regulation of fear and anxiety: an update [PDF]

open access: yes, 2019
Purpose of ReviewAnxiety- and trauma-related disorders are prevalent and debilitating mental illnesses associated with a significant socioeconomic burden.
Papagianni, Eleni P., Stevenson, Carl W.
core   +1 more source

Study of the fragmentation of cannabidiol and derivatives under soft ionization mass spectrometric methods

open access: yes, 2021
Cannabidiol was ionized under Electrospray Ionization Mass Spectrometry (ESI-MS) and Atmospheric Pressure Chemical Ionization Mass Spectrometry (APCI-MS) to obtain precursor ions.
Üneri Haymana, Serra
core  

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