Results 11 to 20 of about 17,947 (225)

Effect of combining CBD with standard breast cancer therapeutics

open access: yesAdvances in Cancer Biology - Metastasis, 2022
Breast cancer is the most common malignancy in women worldwide. Sixty-five percent of breast cancers are estrogen and/or progesterone receptor positive.
Luka Dobovišek   +5 more
doaj   +1 more source

Combination therapy with cannabidiol and chemotherapeutics in canine urothelial carcinoma cells.

open access: yesPLoS ONE, 2021
BackgroundCanine urothelial carcinoma is the most common form of canine bladder cancer. Treatment with chemotherapy has variable response rates leading to most dogs succumbing to their disease within a year.
Jordon M Inkol   +2 more
doaj   +2 more sources

Protective effects of cannabidiol on lesion-induced intervertebral disc degeneration. [PDF]

open access: yesPLoS ONE, 2014
Disc degeneration is a multifactorial process that involves hypoxia, inflammation, neoinnervation, accelerated catabolism, and reduction in water and glycosaminoglycan content.
João W Silveira   +7 more
doaj   +1 more source

CANNABIDIOL- PROVOKES OR TREATS ANXIETY DISORDERS?

open access: yesEuropean Psychiatry, 2023
Introduction After the introduction of proposal regarding cannabidiol for the treatment of some psychiatric disorders including anxiety, there is confusion if cannabidiol use is associated with the provocation of anxiety symptoms or it can be safely ...
H. Arshad   +5 more
doaj   +1 more source

Cannabidiol regulation of learned fear: implications for treating anxiety-related disorders

open access: yesFrontiers in Pharmacology, 2016
Anxiety and trauma-related disorders are psychiatric diseases with a lifetime prevalence of up to 25%. Phobias and post-traumatic stress disorder (PTSD) are characterized by abnormal and persistent memories of fear-related contexts and cues.
Regimantas Jurkus   +5 more
doaj   +1 more source

Cannabidiol markedly alleviates skin and liver fibrosis

open access: yesFrontiers in Pharmacology, 2022
Cannabidiol (CBD) has been suggested as a potential therapy for inflammatory and fibrotic diseases. Cannabidiol was demonstrated to reduce alcohol-induced liver inflammation and steatosis but its specific activity on the fibrotic process was not ...
Carmen del Río   +12 more
doaj   +1 more source

Cannabidiol in the Treatment of Epilepsy [PDF]

open access: yesClinical Drug Investigation, 2021
Anecdotal reports addressing the successful seizure treatment of severe epilepsies with cannabidiol (CBD) have increased both public interest and academic research. Placebo-controlled, randomized, controlled trials proved the efficacy of pharmaceutical-grade CBD in epilepsy treatment, thus leading to pharmaceutical-grade CBD approval by the US Food and
von Wrede, Randi   +2 more
openaire   +2 more sources

Regulation of Innate Lymphoid Cells in Acute Kidney Injury: Crosstalk between Cannabidiol and GILZ

open access: yesJournal of Immunology Research, 2020
Innate lymphoid cells (ILCs) have emerged as largely tissue-resident archetypal cells of the immune system. We tested the hypotheses that renal ischemia-reperfusion injury (IRI) is a contributing factor to polarization of ILCs and that glucocorticoid ...
Babak Baban   +5 more
doaj   +1 more source

Cannabidiol-Loaded Nanoparticles Based on Crosslinked Starch: Anti-Inflammatory Activity and Improved Nose-to-Brain Delivery

open access: yesPharmaceutics, 2023
Cannabidiol (CBD) has previously been shown to inhibit inflammatory cytokine production in both in vitro and in vivo studies of neurodegenerative diseases.
Ilya Eydelman   +5 more
doaj   +1 more source

Enhanced Skin Penetration of Cannabidiol Using Organosilane Particles as Transdermal Delivery Vehicles

open access: yesPharmaceutics, 2023
There is potential for cannabidiol to act as an analgesic, anxiolytic and antipsychotic active ingredient; however, there is a need to find alternate administration routes to overcome its low oral bioavailability.
Zahra Khabir   +5 more
doaj   +1 more source

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