Results 21 to 30 of about 28,895 (261)

Cannabinoids Reduce Melanoma Cell Viability and Do Not Interfere with Commonly Used Targeted Therapy in Metastatic Melanoma In Vivo and In Vitro

Biology, 2023
Background: Cannabinoids are mainly used for recreational purposes, but also made their way into oncology, since these substances can be taken to increase appetite in tumour cachexia.
Georg Richtig, Melanie Kienzl, Sonja Rittchen, David Roula, Jürgen Eberle, Zina Sarif, Martin Pichler, Gerald Hoefler, Akos Heinemann   +8 more
doaj   +1 more source

Cannabinoids and Multiple Sclerosis: A Critical Analysis of Therapeutic Potentials and Safety Concerns

Pharmaceutics, 2023
Multiple sclerosis (MS) is a complicated condition in which the immune system attacks myelinated axons in the central nervous system (CNS), destroying both myelin and axons to varying degrees.
Roua A. Nouh, Ahmed Kamal, Anwar Abdelnaser   +2 more
doaj   +1 more source

Comparative study between effect of Cannabis and Synthetic Cannabinoids on cognitive functions [PDF]

Al-Azhar International Medical Journal, 2022
Background: Synthetic cannabinoid usage is on the rise around the world, and it has become a huge global health issue. Previous studies showed a relationship between synthetic cannabinoids and cognitive function decline either after acute or chronic ...
Mohammed Abdel-Ghany, Mohammed Hamouda, Mohammed Fahmi   +2 more
doaj   +1 more source

Cannabinoids modulate food preference and consumption in Drosophila melanogaster

Scientific Reports, 2021
Cannabinoids have an important role in regulating feeding behaviors via cannabinoid receptors in mammals. Cannabinoids also exhibit potential therapeutic functions in Drosophila melanogaster, or fruit fly that lacks cannabinoid receptors.
Jianzheng He, Alice Mei Xien Tan, Si Yun Ng, Menglong Rui, Fengwei Yu   +4 more
doaj   +1 more source

Regulatory status and research progress in the supervision of cannabinoid compounds in food in some countries and regions

Shanghai yufang yixue, 2023
A group of compounds structurally related to tetrahydrocannabinol or capable of binding to cannabinoid receptors are collectively referred to as cannabinoids.
CHEN Jing, CHEN Yan, SHEN Xiaoqian, CHI Qiuchi, PAN Ying   +4 more
doaj   +1 more source

Cannabinoid and Hyperemesis [PDF]

Mayo Clinic Proceedings, 2012
To the Editor: We read with interest the article by Simonetto et al1 on cannabinoid hyperemesis (CH) that was published in the February 2012 issue of Mayo Clinic Proceedings. Indeed, this entity is underdiagnosed due to a lack of awareness. Marijuana users presenting to the emergency department with nausea, vomiting, and abdominal pain are a common ...
Pallawi, Torka, Rajeev, Sharma
openaire   +2 more sources

Sex Differences in the Behavioral and Synaptic Consequences of a Single in vivo Exposure to the Synthetic Cannabimimetic WIN55,212-2 at Puberty and Adulthood

Frontiers in Behavioral Neuroscience, 2019
Heavy cannabis consumption among adolescents is associated with significant and lasting neurobiological, psychological and health consequences that depend on the age of first use.
Milene Borsoi, Milene Borsoi, Antonia Manduca, Antonia Manduca, Anissa Bara, Anissa Bara, Olivier Lassalle, Olivier Lassalle, Anne-Laure Pelissier-Alicot, Anne-Laure Pelissier-Alicot, Anne-Laure Pelissier-Alicot, Anne-Laure Pelissier-Alicot, Olivier J. Manzoni, Olivier J. Manzoni   +13 more
doaj   +1 more source

Heteroadamantyl Cannabinoids [PDF]

Journal of Medicinal Chemistry, 2010
The aliphatic side chain plays a pivotal role in determining the cannabinergic potency of tricyclic classical cannabinoids. We have synthesized a series of analogues in which the C3 position is substituted either directly or through a one-carbon atom linker with an adamantylamine or with an oxa- or an oxazaadamantane. The oxaadamantane pharmacophore in
Darryl D, Dixon, Divakaramenon, Sethumadhavan, Tore, Benneche, April R, Banaag, Marcus A, Tius, Ganesh A, Thakur, Anna, Bowman, Jodianne T, Wood, Alexandros, Makriyannis   +8 more
openaire   +2 more sources

Synthesis of Six Natural Products Enabled by Selective Hydroxylation of Orcinaldehyde‐Like Substrates With an Enzyme Library

Angewandte Chemie, EarlyView.
Achieving selective (sp3)C–H hydroxylation can streamline the synthesis of complex organic molecules. Biocatalysis presents an opportunity to realize this transformation, however, identifying useful enzymes that enable synthetic strategies can be a challenge due to limitations in enzyme substrate scope.
Gonzalo J. Villegas Rodríguez, Evan O. Romero, Jonathan C. Perkins, Diego N. Rojas, Maximilian S. Hrigora, Alison R. H. Narayan   +5 more
wiley   +2 more sources

The Highs and Lows of Cannabis in Cancer Treatment and Bone Marrow Transplantation

Rambam Maimonides Medical Journal, 2020
In the last decade, we have observed an increased public and scientific interest in the clinical applications of medical cannabis. Currently, the application of cannabinoids in cancer patients is mainly due to their analgesic and anti-emetic effects. The
Osnat Almogi-Hazan, Iman Khuja, Sivan Ritter, Reuven Or   +3 more
doaj   +1 more source