Results 21 to 30 of about 64,716 (311)

Potential of dietary hemp and cannabinoids to modulate immune response to enhance health and performance in animals: opportunities and challenges

Frontiers in Immunology, 2023
Cannabinoids are a group of bioactive compounds abundantly present in Cannabis sativa plant. The active components of cannabis with therapeutic potential are known as cannabinoids.
Faiz-ul Hassan, Faiz-ul Hassan, Chunjie Liu, Maryam Mehboob, Rana Muhammad Bilal, Muhammad Asif Arain, Faisal Siddique, Fengming Chen, Yuying Li, Jingmeng Zhang, Pengjun Shi, Biguang Lv, Qian Lin   +12 more
doaj   +1 more source

The therapeutic aspects of the endocannabinoid system (ECS) for cancer and their development: from nature to laboratory [PDF]

, 2016
The endocannabinoid system (ECS) is a group of neuromodulatory lipids and their receptors, which are widely distributed in mammalian tissues. ECS regulates various cardiovascular, nervous, and immune system functions inside cells.
Botta, Bruno, Czarnecka, Anna M., Khan, Mohammed I., Król, Magdalena, Sobocińska, Anna A., Szczylik, Cezary   +5 more
core   +1 more source

Heteroadamantyl Cannabinoids [PDF]

Journal of Medicinal Chemistry, 2010
The aliphatic side chain plays a pivotal role in determining the cannabinergic potency of tricyclic classical cannabinoids. We have synthesized a series of analogues in which the C3 position is substituted either directly or through a one-carbon atom linker with an adamantylamine or with an oxa- or an oxazaadamantane. The oxaadamantane pharmacophore in
Darryl D, Dixon, Divakaramenon, Sethumadhavan, Tore, Benneche, April R, Banaag, Marcus A, Tius, Ganesh A, Thakur, Anna, Bowman, Jodianne T, Wood, Alexandros, Makriyannis   +8 more
openaire   +2 more sources

Using a global diversity panel of Cannabis sativa L. to develop a near InfraRed-based chemometric application for cannabinoid quantification

Scientific Reports, 2023
C. sativa has gained renewed interest as a cash crop for food, fibre and medicinal markets. Irrespective of the final product, rigorous quantitative testing for cannabinoids, the regulated biologically active constituents of C.
Francine Gloerfelt-Tarp, Amitha K. Hewavitharana, Jos Mieog, William M. Palmer, Felicity Fraser, Omid Ansari, Tobias Kretzschmar   +6 more
doaj   +1 more source

Cannabinoids Reduce Melanoma Cell Viability and Do Not Interfere with Commonly Used Targeted Therapy in Metastatic Melanoma In Vivo and In Vitro

Biology, 2023
Background: Cannabinoids are mainly used for recreational purposes, but also made their way into oncology, since these substances can be taken to increase appetite in tumour cachexia.
Georg Richtig, Melanie Kienzl, Sonja Rittchen, David Roula, Jürgen Eberle, Zina Sarif, Martin Pichler, Gerald Hoefler, Akos Heinemann   +8 more
doaj   +1 more source

Cannabinoids and Multiple Sclerosis: A Critical Analysis of Therapeutic Potentials and Safety Concerns

Pharmaceutics, 2023
Multiple sclerosis (MS) is a complicated condition in which the immune system attacks myelinated axons in the central nervous system (CNS), destroying both myelin and axons to varying degrees.
Roua A. Nouh, Ahmed Kamal, Anwar Abdelnaser   +2 more
doaj   +1 more source

New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites. [PDF]

, 2019
Synthetic cannabinoids (SCs) were initially developed as pharmacological tools to probe the endocannabinoid system and as novel pharmacotherapies, but are now highly abused.
Diao, Xingxing, Huestis, Marilyn A.
core   +2 more sources

Cannabinoids modulate food preference and consumption in Drosophila melanogaster

Scientific Reports, 2021
Cannabinoids have an important role in regulating feeding behaviors via cannabinoid receptors in mammals. Cannabinoids also exhibit potential therapeutic functions in Drosophila melanogaster, or fruit fly that lacks cannabinoid receptors.
Jianzheng He, Alice Mei Xien Tan, Si Yun Ng, Menglong Rui, Fengwei Yu   +4 more
doaj   +1 more source

Regulatory status and research progress in the supervision of cannabinoid compounds in food in some countries and regions

Shanghai yufang yixue, 2023
A group of compounds structurally related to tetrahydrocannabinol or capable of binding to cannabinoid receptors are collectively referred to as cannabinoids.
CHEN Jing, CHEN Yan, SHEN Xiaoqian, CHI Qiuchi, PAN Ying   +4 more
doaj   +1 more source

Comparative study between effect of Cannabis and Synthetic Cannabinoids on cognitive functions [PDF]

Al-Azhar International Medical Journal, 2022
Background: Synthetic cannabinoid usage is on the rise around the world, and it has become a huge global health issue. Previous studies showed a relationship between synthetic cannabinoids and cognitive function decline either after acute or chronic ...
Mohammed Abdel-Ghany, Mohammed Hamouda, Mohammed Fahmi   +2 more
doaj   +1 more source