Results 41 to 50 of about 12,540 (181)

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Development and Optimization of a Germination Assay and Long-Term Storage for Cannabis sativa Pollen

open access: yesPlants, 2020
Pollen viability and storage is of great interest to cannabis breeders and researchers to maintain desirable germplasm for future use in breeding or for biotechnological and gene editing applications.
Daniel Gaudet   +4 more
doaj   +1 more source

Cannabis sativa L. alleviates loperamide-induced constipation by modulating the composition of gut microbiota in mice

open access: yesFrontiers in Pharmacology, 2022
MaZiRenWan (MZRW) is the most frequently used Traditional Chinese Medicine formula to treat chronic constipation, Cannabis sativa L. is regarded as a monarch drug in MZRW. However, the targets of Cannabis sativa L.
Rong Li   +4 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Análise da utilização da Cannabis sativa na prática da clínica veterinária de pequenos animais: uma visão atual

open access: yesPubvet
No cenário atual, a Cannabis sativa tem tido um importante destaque devido ao crescente uso de seus componentes na terapêutica de diversas patologias, tanto na medicina humana como na medicina veterinária.
Hellen Thawane Duarte, Luciana de Souza
doaj   +1 more source

A neurotoxicidade da Cannabis sativa e suas repercussões sobre a morfologia do tecido cerebral

open access: yesABCS Health Sciences, 2014
Para a compreensão das repercussões psicológicas e comportamentais verificadas em usuários de Cannabis sativa, experimentos têm sido desenvolvidos analisando a relação entre a intensidade do uso da droga e biomarcadores de lesão e inflamação. Dessa forma,
Bárbara da Silva Santos   +1 more
doaj   +1 more source

Protective effects of extracellular vesicle‐like nanoparticles derived from Cannabis sativa adventitious roots against UVB‐induced damage in human keratinocytes

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Cannabis sativa root‐derived extracellular vesicle‐like nanoparticles (CA‐NPs) were isolated from adventitious root cultures and subjected to physicochemical characterization. Upon UVB exposure, keratinocytes exhibited increased ROS generation, apoptosis and MAPK activation, leading to oxidative stress and skin damage.
Dong Ho Bak   +5 more
wiley   +1 more source

Assessment of Cannabidiol Supplements Use in Small Animals Practice in Portugal

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT This study aimed to assess the current use of cannabidiol supplements (CBDS) by Portuguese small animal veterinary practitioners. An anonymous online survey questioning the frequency of CBDS use, purpose of use and the perceived outcome was developed using Microsoft Forms, and targeted veterinarians currently working in small animal clinics in
Maria Inês Santos, Ana Luísa Lourenço
wiley   +1 more source

Effect of hydroalcoholic extract of Cannabis sativa on cell survival and differentiation of mesenchymal stem cells derived from human adipose tissue to osteoblast-like cells

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2019
Background and Objective: The resin secretions of Cannabis sativa are called Hashish, which has medicinal and psychological properties. The most important psychoactive compound of this plant is THC (Delta-9-Tetrahydrocannabinol), which can stimulate ...
Mehregan Jamshidi   +3 more
doaj  

Biotransformation of monoterpenols upon pre‐treatment with oregano essential oil vapour alleviates downy mildew susceptibility in grapevine leaves

open access: yesPlant Biology, EarlyView.
Pre‐treatment of grapevine plants with oregano essential oil vapour alleviates downy mildew susceptibility by accumulation of monoterpenol glycosides. Abstract Grapevine downy mildew, caused by the oomycete Plasmopara viticola, is a destructive disease that causes major economic losses as most elite grapevine cultivars are susceptible to this pathogen.
J. R. P. E. Mars   +6 more
wiley   +1 more source

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