Results 11 to 20 of about 287 (112)

Perfiles de un debate sobre la Passio Mantii [PDF]

open access: yes, 2018
Despite the current historiography places the Passio Mantii in the Visigothic period, nowadays there is some dissenting voice that, with mainly philological arguments, claims that it should be «transferred» to the Spanish Mozarabic period.
González Salinero, Raúl   +1 more
core   +2 more sources

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes   +75 more
wiley   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro   +7 more
wiley   +1 more source

Communities of the blessed : the origins and development of regional churches in Northern Italy, c.250 - 381 C.E. [PDF]

open access: yes, 2012
This thesis argues that the origins and evolution of Christian communities in Northern Italy between c. 250 and 381 are comprehensible only within the region's social environment.
Humphries, Mark
core  

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

open access: yesAdvanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen   +17 more
wiley   +1 more source

Society and the inquisition in Malta 1743-1798 [PDF]

open access: yes, 1998
The thesis falls into two main sections. It endeavours to analyse the major aspects of Maltese society in the second half of the eighteenth century as they emerge from a close scrutiny of the Archives of the Inquisition in Malta.
Ciappara, Frans
core  

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

open access: yesAdvanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg   +18 more
wiley   +1 more source

Dorothy Wordsworth and Hartley Coleridge : the poetics of relationship [PDF]

open access: yes, 2009
My thesis studies Hartley Coleridge and Dorothy Wordsworth to redress the unjust neglect of Hartley’s work, and to reach a more positive understanding of Dorothy’s conflicted literary relationship with William Wordsworth and Samuel Taylor Coleridge.
Healey, Nicola, 1981-
core  

Accurately Deciphering Tissue Heterogeneity From Spatial Multi‐Modal and Multi‐Omics With STransformer

open access: yesAdvanced Science, EarlyView.
STransformer is a unified deep learning framework designed to seamlessly accommodate a comprehensive landscape of spatial data. By simultaneously capturing short‐range cellular interactions and tissue‐wide semantic patterns, it extracts robust representations to accurately dissect complex tissue heterogeneity.
Xingyi Li   +9 more
wiley   +1 more source

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