Results 91 to 100 of about 299,088 (201)

Strawberry Notch 1 Acts as a Transcriptional Regulator Driving Oncogenic Programs in Liver Carcinogenesis

Advanced Science, EarlyView.
This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche, Raisatun Nisa Sugiyanto, Kira Gür, Alina Krumme, Maxime Le Marois, Angelika Fraas, Aslihan Inal, Mario Huerta, Vanessa Henriques, Eva Eiteneuer, Thomas Albrecht, Alphonse Charbel, Michael T. Dill, Carsten Sticht, Carolina De La Torre, Stefan Pusch, Arianeb Mehrabi, Kai Breuhahn, Junfang Ji, Peter Schirmacher, Benjamin Goeppert, Stephanie Roessler   +21 more
wiley   +1 more source

Early recurrence of left atrial myxofibrosarcoma: A case report of a clinical and histopathologic challenge. [PDF]

J Cardiothorac Surg
Motta-Amar A, Maldonado-Cañón K, Niño S, Molina G, Rodríguez-Sarmiento JL, Gómez-Lopera N, Rojas Aguirre FA, Maldonado-Escalante J.   +7 more
europepmc   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Low-dose radiotherapy for benign conditions: management of persistent inguinal lymphorrea. [PDF]

Radiat Oncol
Cañón V, Anchuelo J, Laborda C, Galán A, Rivero AL, Pinto F, García M, Navarrete P, Galdós P, Aliaga A, Ayete Andreu A, García C, Liria G, Cerrolaza M, Fabregat R, Pla CC, Prada PJ.   +16 more
europepmc   +1 more source

A Comparative Analysis of a Corporation\u27s Right Against Self-Incrimination [PDF]

, 1995
Baron, Jens Malte, Fietkau, K., Kluwig, D., Lüscher, Bernhard, Marquardt, Yvonne, Pfaff, C.   +5 more
core   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Novel use of <i>Quillaja saponaria</i> extracts to prevent viral infections in Atlantic salmon: <i>in vitro</i> ISAv and IPNv inhibition and <i>in vivo</i> protection against IPNv. [PDF]

Front Vet Sci
Schlotterbeck T, Cortés H, Cañon-Jones H, San Martín R, Padilla L, Castillo-Ruiz M.   +5 more
europepmc   +1 more source

Keeping Mud Off the Bench: The First Amendment and Regulation of Candidates’ False or Misleading Statements in Judicial Elections [PDF]

, 2001
Long, Adam R.
core   +1 more source

Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly

Advanced Science, EarlyView.
Populations at the invasion front of Bactrocera dorsalis adapt through reduced phenotypic and gene expression plasticity, a phenomenon likely to be driven by genetic assimilation. We identify a key miRNA‐mediated regulatory axis, in which miR‐276b post‐transcriptionally represses thw, a conserved chitin‐binding gene critical to the cold‐tolerance ...
Yan Zhao, Juntao Hu, Juan Du, Shaokun Guo, Youming Hou, Zhihong Li   +5 more
wiley   +1 more source

Spatiotemporal infestation patterns of Aceria litchii Keifer (Acari: Eriophyidae) in a lychee orchard in South Florida. [PDF]

Sci Rep
Ataide LMS, Riley S, Dutra J, De Giosa M, Canon MA, Della Vechia JF, Tassi AD, Villamarin P, Crane JH, Carrillo D, Revynthi AM.   +10 more
europepmc   +1 more source