Results 171 to 180 of about 62,166,301 (209)

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

Risk factors and outcomes of healthcare-associated infections in a Brazilian intensive care unit: A cross-sectional study. [PDF]

Belitung Nurs J
de Sousa Moura AM, de Sousa ÁFL, de Carvalho HEF, Madeira MZA, Freitas DRJ, Lima ACM, Carneiro LM, Valim MD, Junior AGDS, Batista OMA.   +9 more
europepmc   +1 more source

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

Advanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li, Ying Liu, Longsheng Xing, Xianliang Huang, Yingming Sun, Lei Yue, Yuze Zhang, Huilong Du, Bing Chen   +8 more
wiley   +1 more source

A computer-aided method for the automatic localization of the left ventricular long axis on coronary computed tomography angiography. [PDF]

Quant Imaging Med Surg
Li S, Ma T, Guo Y, Xiao Y, Yang A, Xu Y, Li S, He Y.   +7 more
europepmc   +1 more source

Probing Electrocatalyst Design for Product Selectivity in CO2 Reduction

Advanced Science, EarlyView.
Selective CO2 electroreduction is controlled by catalyst structure, dynamic surface reconstruction, adsorbate interactions, and reaction microenvironment. This review summarizes Cu‐ and non‐Cu‐based catalysts, single‐atom and molecular systems, degradation pathways, and operando/computational strategies for steering CO2RR toward hydrocarbons ...
Suvodeep Sen, Bapan Biswas, Apinya Ngoipala, Julia Wiktor, Ujjwal Pal, Shalini Singh   +5 more
wiley   +1 more source

Patient Centring in CT: An International Survey of Clinical Practice and Future Directions. [PDF]

J Med Radiat Sci
Hadi YH, Bani-Ahmad M, Moore N, Clark KR, Al-Hayek Y, Albeshan SM, Alghamdi SB, Precht H, England A, McEntee M.   +9 more
europepmc   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Cyclamen persicum Mill. and Leontice leontopetalum L., common vernacular names - and their relation to washing, incense and the unexplained 'Jordan Dome'. [PDF]

J Ethnobiol Ethnomed
Dafni A, Khatib S', Böck B.
europepmc   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

Advanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel   +6 more
wiley   +1 more source

Fine Needle Aspiration Biopsy of Thyroid Nodules Using Aspiration vs. Capillary Technique: Our Experience. [PDF]

Diagnostics (Basel)
Saenz De Argandoña Echeverría O, Rodríguez Y, Pariente JC, Vivó F, Rodrigo M, Calvo Porcel A, Martín Vidal G, Squarcia M, Puig J, Bargalló N, Medrano-Martorell S.   +10 more
europepmc   +1 more source