Results 181 to 190 of about 62,166,301 (209)

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

Comparative Adaptive Mechanisms of Two Indigenous Goat Genetic Resources Under Simulated Water Scarcity. [PDF]

Animals (Basel)
Akinmoladun OF, Mnyobisi R, Mpetile Z.
europepmc   +1 more source

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

Advanced Science, EarlyView.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang, Ting Wu, Feizuo Wang, Boyang Wang, Xin Yu Wong, Senfeng Zhang, Shengsheng Ma, Yao Liu, Fangyao Yao, Zhifeng Zeng, Siyuan Yang, Kunming Liu, Qi Wang, Yilong Wang, Yunxiang Zang, Xiaolong Wang, Xingxu Huang, Shao Li, Quanquan Ji, Tao Hu, Chunyi Hu   +20 more
wiley   +1 more source

Early prescription of quadruple therapy in acute decompensated heart failure with reduced ejection fraction: A propensity score-matched analysis. [PDF]

ESC Heart Fail
Echeverría LE, Rojas LZ, Serrano-García AY, Botero D, García-Rueda KA, Torres-Bustamante Á, Cañón-Gómez DI, Salcedo JS, Hurtado-Ortiz A, Rodríguez JA, Gómez-Ochoa SA.   +10 more
europepmc   +1 more source

Comparing YOLO and U-net deep learning algorithms in chronic wound image segmentation. [PDF]

BMC Med Imaging
Marchal I, Ali Z, Ammi H, Smet S, Van de Voorde L, Varon C, Ngan Yamb MA, Yunda Sangoluisa JA, Quitin F, Nonclercq A.   +9 more
europepmc   +1 more source

A Serotoninomic Framework for Reproductive and Integrative Toxicology: Molecular, Neurochemical, and Behavioural Perspectives on Permethrin Exposure. [PDF]

Toxics
Jiménez-Trejo F, Carmona-Aparicio L, Coballase-Urrutia E, Jiménez-García KL, Arriaga-Canon C, Herrera LA.   +5 more
europepmc   +1 more source

Causal inference and digital twins: a roadmap for the future of clinical trials. [PDF]

NPJ Digit Med
Ruhrberg Estévez S, Peck R, McKinney E, Weatherall J, Bailey S, Rochon J, Anagnostopoulos C, Marquet P, Wood A, Best N, Amad H, Piskorz J, Kacprzyk K, Salama R, Gunther C, Frau F, Pugeat A, Hernandez R, van der Schaar M.   +18 more
europepmc   +1 more source

Reasoning and reconciliation in twelfth-century Anglo-Norman legal writing. [PDF]

Compara Leg Hist (Hart Publ (Oxf Engl))
White SB.
europepmc   +1 more source

Discovery of a novel <i>Keithomyces</i> species isolated from the sclerotia and a new <i>Papiliomyces</i> from Southwest China: Integrated taxonomy based on morphology and phylogeny. [PDF]

MycoKeys
Tang D, Chen H, Huang O, Tao L, Li QR, Wang Y, Sheng X.   +6 more
europepmc   +1 more source

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Why is classical theory classical? Theorizing the canon and canonizing Du Bois

Journal of Classical Sociology, 2021
Michael Burawoy
exaly