Results 21 to 30 of about 62,166,301 (209)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Foundations of a Sociology of Canon Law [PDF]
, 2022 This "Open Access" book investigates the legal reality of the church through a sociological lens and from the perspective of canon law studies, the discipline which researches the law and the legal structure of the Catholic Church.
Hahn, Judith
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
El canon y la tradición judeocristiana
, 2015 Si nuestra noción de clásico irremediablemente remite a la Antigüedad grecolatina, nuestra noción de canon hace lo propio con la tradición judeocristiana. La propia palabra canon procede del griego kanwn, ’vara, caña’ y, por metonimia, ‘medida’, y este a
Carmen Morán
core +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Los estudios socioculturales: ¿hacia un nuevo canon? [PDF]
, 2001 De vez en cuando hay críticos renombrados que se conuelana sí mismos y a sus públicos descanando el deatesobre el canon como una absurdidad más entre lasmodas culturales contemporáneas, o atribuyéndole un papelinsignificante en la historia intelectual ...
Gorak, Jan, Goran, Jan
core
Travesías pedagógicas del canon en músicas de Latinoamérica
, 2022 Este dossier reúne —mediante el estudio de géneros, personalidades, instituciones y obras musicales que provienen de Argentina, Chile, Colombia y Brasil— un conjunto de artículos procedentes, en todos los casos, de investigaciones doctorales en curso.
Mansilla, Silvina Luz María
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source