Results 21 to 30 of about 299,980 (229)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Legal Classics: After Deconstructing the Legal Canon [PDF]
, 1994 The debate over the canon has gripped the University in recent years. Defenders of the canon argue that canonical texts embody timeless and universal themes, but critics argue that the process of canonization subordinates certain people and viewpoints ...
Mootz, Francis J., III
core +2 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
The Ghost in the Courtroom: When Opinions Are Adopted Verbatim from Prosecutors [PDF]
, 2014 Judicial opinions captivate the legal community, serving as a hub for teaching new lawyers and developing the law. These opinions also provide a method for the justice system to communicate with the people it serves—both the parties to the cases and the ...
Hansson, Per-Olof, Jobe, William
core +2 more sources
Caldasia, 2006 En la vegetación de la cuenca media del cañón del río Chicamocha entre los 500y los 1170 m de altitud, en los municipios de Cepitá y Piedecuesta (Inspección dePolicía de Pescadero), en Santander-Colombia, el tipo fisionómico dominante es elmatorral ...
ALBESIANO SOFÍA +1 more
doaj
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
CHIMERA: a wide-field, multi-color, high-speed photometer at the prime focus of the Hale telescope
, 2016 The Caltech HIgh-speed Multi-color camERA (CHIMERA) is a new instrument that has been developed for use at the prime focus of the Hale 200-inch telescope. Simultaneous optical imaging in two bands is enabled by a dichroic beam splitter centered at 567 nm,
Gardner, Paul +9 more
core +1 more source
The significance of the Carolingian advocate [PDF]
, 2009 This article argues that ninth-century advocates in the Frankish world deserve more attention than they have received. Exploring some of the wealth of relevant evidence, it reviews and critiques both current historiographical approaches to the issue ...
West, Charles
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Postprint Copy of Years of Teaching Dangerously: Interfacing Thomas Cromwell in Canon and Fandom, Michael Drayton, “W.S.,” and Hilary Mantel [PDF]
, 2016 When Sir Thomas Bodley founded the Bodleian Library, he sought to keep “baggage books,” “riff-raff books,” and distasteful literature off the shelves. The question of keeping literature in or out of a library or canon is never simply about literature; it
Laurie Ringer
core +1 more source