Results 21 to 30 of about 279,261 (248)

Elucidating and Collating the True Scriptures: A Study of the Newly Discovered Qing-Dynasty Editions of the Nanbei dou jing chanwei

open access: yesReligions
The veneration of the Southern and Northern Dippers stands at the heart of the Daoist tradition of astral worship, and the compilation of the Nanbei dou jing (Scriptures of the Southern and Northern Dippers) during the Northern Song dynasty marks a ...
Qinsheng Shi
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Systemic Innovation Through Non-Dominant Firms: Dual-Path R–S–C Mechanisms in China’s Autonomous Driving Ecosystem

open access: yesSystems
How non-dominant specialized firms sustain systemic innovation influence in modular service ecosystems without occupying architectural control positions remains theoretically underdeveloped. This study develops a dual-path Resource–Strategy–Capability (R–
Shaozhen Hong, Yingqi Liu
doaj   +1 more source

Codification of administrative law in Sweden

open access: yes, 2023
In this chapter, the codification of administrative law in Sweden is presented. As will be shown, Swedish administrative law has a long history and is well developed in terms of codification.
Reichel, Jane,, Ribbing, Michaela,
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Connected Permutations of Vertices for Canonical Form Detection in Graph Mining

open access: yesRevista Cubana de Ciencias Informáticas, 2015
Checking redundancies is one of the most significant tasks in graph mining. Canonical forms of graphs are widely used to guarantee and speed up this kind of task.
Andrés Gago-Alonso
doaj  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

PerseusDL/canonical-latinLit: 0.0.4734888628

open access: yes, 2023
XML Canonical resources for Latin ...
Marius Jøhndal   +19 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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