Results 41 to 50 of about 268,889 (246)

PerseusDL/canonical-latinLit: 0.0.3961670606

open access: yes, 2023
XML Canonical resources for Latin ...
Marius Jøhndal   +19 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

The Canons of Indian Treaty and Statutory Construction: A Proposal for Codification

open access: yesUniversity of Michigan Journal of Law Reform
This Note argues that the canons of construction should play a central role in the interpretation of Indian treaties and statutes. The Note proposes revitalization of the canons through congressional action codifying the rules of construction into federal law.
openaire   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

LAS OBSERVACIONES DE LOS OBISPOS CHILENOS A LOS PROYECTOS DE LIBRO IV, DE DELICTIS ET POENIS, Y LIBRO V, DE IUDICIIS ECCLESIASTICIS, DEL CÓDIGO DE DERECHO CANÓNICO DE 1917 THE CHILEAN BISHOPS’ COMMENTARIES TO THE PROJECTS OF BOOK IV, DE DELICTIS ET POENIS, AND BOOK V, DE IUDICIIS ECCLESIASTICIS, FOR THE NEW CANONICAL LAW CODE OF 1917

open access: yesRevista Chilena de Derecho, 2009
La redacción del primer Código de Derecho Canónico que tuvo la Iglesia latina fue ordenada por el papa san Pío X en 1904. La tarea codificadora, empero, no fue obra de un grupo cerrado de expertos, sino que tuvo en cuenta el parecer del episcopado latino,
Carlos Salinas Araneda
doaj  

PerseusDL/canonical-latinLit: 0.0.5580293955

open access: yes, 2023
XML Canonical resources for Latin ...
Marius Jøhndal   +20 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

PerseusDL/canonical-latinLit: 0.0.3370466766

open access: yes, 2022
XML Canonical resources for Latin ...
Marius Jøhndal   +19 more
core   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

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