Results 61 to 70 of about 345 (202)
Symmetrical distributions of aminoacyl-tRNA synthetases during the evolution of the genetic code. [PDF]
Theory Biosci, 2023 José MV +3 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen +6 more
wiley +1 more source
The interoperability between the Spanish version of the International Classification of Diseases and ORPHAcodes: towards better identification of rare diseases. [PDF]
Orphanet J Rare Dis, 2021 Rico J +6 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang +13 more
wiley +1 more source
Revista de Derecho (Coquimbo), 2011 La redacción del primer Código de Derecho Canónico que tuvo la Iglesia latina fue ordenada por el papa san Pío X en 1904. La tarea codificadora, empero, no fue obra de un grupo cerrado de expertos, sino que tuvo en cuenta el parecer del episcopado latino, el que fue consultado en dos momentos diferentes; en ambos fueron consultados los obispos de ...
openaire +1 more source
Advanced Healthcare Materials, EarlyView.A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter +5 more
wiley +1 more source
Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy
Advanced Healthcare Materials, EarlyView.This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su +8 more
wiley +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Assembling a True “Olympic Gel” From over 16 000 Combinatorial DNA Rings
Advanced Materials, EarlyView.Olympic gels are an elusive class of soft matter, consisting of molecular networks held together purely by mechanically interlocked rings. Their topological structure promises unique properties and functions, but their synthesis has proven notoriously difficult.
Sarah K. Speed +9 more
wiley +1 more source