Results 71 to 80 of about 268,889 (246)
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Watermarking using similarities based on fractal codification [PDF]
, 2012 This paper describes a digital watermarking scheme based on fractal codification for 8-bit gray scale images; it replaces range blocks by modified blocks according to the watermark bit being embedded.
CLAUDIA FEREGRINO URIBE +2 more
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Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
FEBS Open Bio, EarlyView.The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
Fourier integrals and a new representation of Maslov's canonical operator near caustics [PDF]
, 2013 We suggest a new representation of Maslov's canonical operator in a neighborhood of the caustics using a special class of coordinate systems (\eikonal coordinates") on Lagrangian ...
Dobrokhotov, Sergey +2 more
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
XSEDE Canonical Use Cases [PDF]
, 2013 This document is both a user-facing document (publically accessible) and an internal working document intended to define basic user needs and use cases within the overall activities of XSEDE.Submitted by Janet Brown (brown@psc.edu) on 2013-04-26T02:39 ...
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Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source
Interpretation and exegesis: An investigation into the canonical approach of B. S. Childs [PDF]
, 1999 We begin this study by delineating the canonical approach pioneered by B. S. Childs. Five critical perspectives on Childs' work follow raising important hermeneutical problems. M. G. Brett, C. J. Scalise and P. R.
Wilson, Norman Samuel
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