Results 41 to 50 of about 490,920 (259)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Dimensionality in canonical correlation of settlements characteristics and levels of infrastructure in rural Akwa Ibom State, Nigeria in 2014 [PDF]

open access: yesIranian Journal of Health, Safety and Environment, 2015
This study examines the relationship between rural settlements characteristics and access levels to infrastructural facilities in Akwa Ibom State. A total of 50 rural settlements were randomly selected and utilized for this study.
Uwem Ituen, Jacob Atser
doaj   +1 more source

Canonical Correlation Analysis of Global Climate Elements and Rainfall in the West Java Regions

open access: yesDesimal, 2020
Indonesia has a diversity of climate influenced by several global phenomena such as El Nino Southern Oscillation (ENSO), Indian Ocean Dipole (IOD), and Asian-Australian Monsoon.
Arisya Maulina Bowo   +2 more
doaj   +1 more source

Ensemble canonical correlation analysis

open access: yesApplied Intelligence, 2013
Canonical Correlation Analysis (CCA) aims at identifying linear dependencies between two different but related multivariate views of the same underlying semantics. Ignoring its various extensions to more than two views, CCA uses these two views as complex labels to guide the search of maximally correlated projection vectors (covariates). Therefore, CCA
Sakar, C. Okan   +2 more
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

An empirical study on the relationship between logistics performance and education

open access: yesBusiness, Management and Education, 2015
Logistics occupations require skills that involve blue- and white-collar activities and different levels of educational skills. With the increase in global trade and competition, the varying skills necessary for different parts of the logistics sector ...
Turkay Yildiz
doaj   +1 more source

Person re-identification by robust canonical correlation analysis [PDF]

open access: yes, 2015
Person re-identification is the task to match people in surveillance cameras at different time and location. Due to significant view and pose change across non-overlapping cameras, directly matching data from different views is a challenging issue to ...
An, L, Bhanu, B, Yang, S
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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