Results 51 to 60 of about 496,805 (322)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Quantum canonical ensemble and correlation femtoscopy at fixed multiplicities

open access: yes, 2016
Identical particle correlations at fixed multiplicity are considered by means of quantum canonical ensemble of finite systems. We calculate one-particle momentum spectra and two-particle Bose-Einstein correlation functions in the ideal gas by using a ...
Akkelin, S. V., Sinyukov, Yu. M.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Application of Canonical Correlation to Two-Dimensional Contingency Tables [PDF]

open access: yesTutorials in Quantitative Methods for Psychology, 2010
This paper re-introduces and demonstrates the use of Mickey’s (1970) canonical correlation method in analyzing large two-dimensional contingency tables. This method of analysis supplements the traditional analysis using the Pearson chi-square.
Alberto F. Restori   +2 more
doaj  

Determination of the Relationship Between Ultrasonic Measurements at Different Fattening Times and Carcass Properties

open access: yesTürkiye Tarımsal Araştırmalar Dergisi, 2020
This study was conducted to estimate the relationships between the ultrasonic measurements and carcass characteristics of Akkaraman lambs at different intensive feeding periods with a multivariate correlation (canonical).
Yasin ALTAY   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Estimating the Number of Significant Canonical Coordinates

open access: yesIEEE Access, 2019
This study proposes a novel model selection criterion for dimensionality estimation in canonical correlation analysis (CCA), which can be used to estimate the number of correlated components between two sets of multivariate vectors, particularly in the ...
Abd-Krim Seghouane, Navid Shokouhi
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Image dehazing using two‐dimensional canonical correlation analysis

open access: yesIET Computer Vision, 2015
Image dehazing is an important issue that interests both image processing and computer vision. In this study, image dehazing is modelled as an example‐based learning problem, and a novel dehazing algorithm using two‐dimensional (2D) canonical correlation
Liqian Wang, Liang Xiao, Zhihui Wei
doaj   +1 more source

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