Group sequential clinical trial designs for composite endpoints incorporating recurrent and terminal events. [PDF]
Lian Q +5 more
europepmc +1 more source
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu +10 more
wiley +1 more source
Factors associated with poor cardiometabolic control in patients with type 2 diabetes: a Lasso-Firth penalized regression analysis. [PDF]
Yang W +14 more
europepmc +1 more source
Evidence for Itinerant Ferromagnetic Flat Bands Producing Large Transverse Responses
Itinerant ferromagnetic flat bands are demonstrated in GdCo5 with a high Curie temperature of 940K, a stacked honeycomb–kagome lattice, through angle‐resolved photoemission spectroscopy and magneto‐thermoelectric measurements. These topological flat bands generate large Berry curvaturte, producing gigantic anomalous Nernst effect with record‐high ...
Susumu Minami +15 more
wiley +1 more source
Multivariate associations between sleep patterns and self-regulation in adolescence: Canonical correlation analysis across ABCD and NCANDA cohorts. [PDF]
Gunawan T +5 more
europepmc +1 more source
Closed‐Loop Solid‐State Synthesis Planning for Materials Discovery With Large Language Models
Leveraging literature data, we build a large‐language‐model‐driven workflow that extracts synthesis steps from 4407 papers, retrieves similar precedents, and generates candidate solid‐state synthesis recipes. The system benchmarks against ground‐truth and then operates in a closed loop with experiments to synthesize oxy‐selenide electrolyte materials ...
Dong Won Jeon +9 more
wiley +1 more source
High-dimensional asymptotic expansions for the distributions of canonical correlations
This paper examines asymptotic distributions of the canonical correlations between and with q [infinity] and c=p/n-->c0[set membership, variant][0,1), assuming that and have a joint (q+p)-variate normal distribution. An extended Fisher's z-transformation
Sakurai, Tetsuro, Fujikoshi, Yasunori
core
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma +15 more
wiley +1 more source
Multivariate associations between systemic inflammation, metabolic dysregulation, and cognitive performance in project FRONTIER. [PDF]
Dhanasekara CS +2 more
europepmc +1 more source
Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello +5 more
wiley +1 more source

