Results 111 to 120 of about 1,601,992 (295)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
CREF-Lang: A domain-specific language and compiler for cross-domain cascade-risk notation
Cascading risk crosses domains, yet the tools analysts use, risk registers, fault-tree analysis, bow-tie diagrams, describe failure inside one system rather than propagation across systems.
Trond Arne Undheim
doaj +1 more source
De la psychanalyse au happening
This article seeks to analyse certain aspects of the reception of Lacan’s theories by the Argentinian literary avant-garde in the nineteen-sixties. It highlights the shifts and deformations that accompanied this cultural transfer, which was more than ...
Julio Premat
doaj +1 more source
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
PerseusDL/canonical-latinLit: 0.0.9333749882
XML Canonical resources for Latin ...
Marius Jøhndal +22 more
core +1 more source
This paper presents the names adopted by monks of the (canonical) Premonstratensian Order at Jászóvár during the 19th century, after the 1802 restitution of the Order.
Gasparics, Gyula
doaj
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Folk Calendar of the Kostroma Region. I : Spring-Summer Cycle
This publication presents a collection of materials on the chrononymy of the Kostroma Region from the 20th and 21st centuries. The field data were collected by the Toponymic Expedition of Ural University between 2003 and 2024. The corpus of chrononyms is
Valeria Stanislavovna Kuchko +1 more
doaj +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source

