Results 111 to 120 of about 1,601,992 (295)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

CREF-Lang: A domain-specific language and compiler for cross-domain cascade-risk notation

open access: yesSoftwareX
Cascading risk crosses domains, yet the tools analysts use, risk registers, fault-tree analysis, bow-tie diagrams, describe failure inside one system rather than propagation across systems.
Trond Arne Undheim
doaj   +1 more source

De la psychanalyse au happening

open access: yesMélanges de la Casa de Velázquez, 2008
This article seeks to analyse certain aspects of the reception of Lacan’s theories by the Argentinian literary avant-garde in the nineteen-sixties. It highlights the shifts and deformations that accompanied this cultural transfer, which was more than ...
Julio Premat
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

PerseusDL/canonical-latinLit: 0.0.9333749882

open access: yes
XML Canonical resources for Latin ...
Marius Jøhndal   +22 more
core   +1 more source

A jászóvári premontrei kanonokrend szerzetesrendi nevei az 1802-es visszaállítást követő évszázadban [Monastic names in the Premonstratensian Order at Jászóvár in the century following the 1802 restitution of the Order]

open access: yesNévtani Értesítő, 2014
This paper presents the names adopted by monks of the (canonical) Premonstratensian Order at Jászóvár during the 19th century, after the 1802 restitution of the Order.
Gasparics, Gyula
doaj  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Folk Calendar of the Kostroma Region. I : Spring-Summer Cycle

open access: yesВопросы ономастики
This publication presents a collection of materials on the chrononymy of the Kostroma Region from the 20th and 21st centuries. The field data were collected by the Toponymic Expedition of Ural University between 2003 and 2024. The corpus of chrononyms is
Valeria Stanislavovna Kuchko   +1 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

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