Results 31 to 40 of about 1,601,992 (295)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A Review: Stories of wheels within wheels - looted art at documenta 14
Journal for Art Market Studies, 2018 The recent documenta 14 (2017) addressed the question of art theft and war spoliations, taking as its point of departure the case of Cornelius Gurlitt (1932-2014).
Eleonora Vratskidou
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Trails of Cultural Memory: Rediscovering Shylock as a Father Figure in the 21st Century
Metacritic Journal for Comparative Studies and Theory, 2021 Given that in the last few decades theories of adaptation have advanced enormously, with such names as Linda Hutcheon setting the theoretical premise of these ideas, it is essential to see how certain aspects present in canonical texts have been ...
Elena Ancuța Ștefan
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
PerseusDL/canonical-latinLit: 0.0.4885091769
, 2023 XML Canonical resources for Latin ...
Marius Jøhndal +19 more
core +1 more source
Name Day in Bulgaria in the Light of Ecclesiastical and Secular Practice
Известия Уральского федерального университета. Серия 2: Гуманитарные наукиThis article presents an ethnolinguistic analysis of the phenomenon of Bulgarian name days, which are experiencing a remarkable boom in the twenty-first century, supported by the mass media and the Internet.
Irina Aleksandrovna Sedakova
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
PerseusDL/canonical-latinLit: 0.0.5258643976
, 2023 XML Canonical resources for Latin ...
Marius Jøhndal +19 more
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source