Results 111 to 120 of about 18,001 (307)

The competence in innovation and entrepreneurship education among Chinese university teachers: a latent profile analysis

Frontiers in Psychology
With the rapid expansion of innovation and entrepreneurship education (IEE), understanding the competencies of university teachers in this field has become increasingly important.
Wenyi Zhang, Huiqing Li, Xudan Zhang, Zhiying Yang, Yingzhi He   +4 more
doaj   +1 more source

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

Advanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li   +14 more
wiley   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau

Advanced Science, EarlyView.
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun, Yang Liu, Qiuzhi Zhou, Qingyuan Hu, Weixia Wang, Yue Xiao, Jingfen Su, Guanting Liu, Miaomiao Sun, Lixia Chen, Hua Li, Ying Yang, Jian‐Zhi Wang   +12 more
wiley   +1 more source

Reversible Exfoliation‐Aggregation Dynamics in Ionic COFs for Tunable Interfacial Catalysis

Advanced Science, EarlyView.
A unique ionic covalent organic framework (I‐4) exhibits unprecedented concentration‐dependent dynamic behavior in water, undergoing reversible transitions between aggregation and exfoliation. This enables fully controllable, bidirectional modulation of its particle size and surface micro‐environment.
Jilu Yang, Xiaofei Zhang, Yue Li, Yuping Cao, Zhaowei Jia, Bo Li, Haitao Feng, Xiaoqiang Cui, Wenwu Qin   +8 more
wiley   +1 more source

Fabrication of Composite Cathode for All‐Solid‐State Sodium Batteries

Advanced Energy Materials, EarlyView.
The design of composite cathodes for all‐solid‐state sodium batteries must address three critical challenges—interfacial side reactions, interfacial delamination, and highly tortuous transport pathways. This work outlines structural and interfacial strategies to optimize ion transport and mechanical stability, enabling durable, and high‐performance ...
Gaoming Sun, Yuan Ma, Hehe Zhang, Shengan Wu, Shiyong Chu, Stefano Passerini, Yanjiao Ma   +6 more
wiley   +1 more source

Design Principles of Electrocatalysts for Industrial‐Scale Water Electrolysis

Advanced Energy Materials, EarlyView.
This Review distills electrocatalyst design for industrial‐scale water electrolysis into integrated principles linking active‐site engineering, phase and lattice modulation, interfacial microenvironment regulation and mass‐transport control. By connecting catalyst families with HER/OER mechanisms and practical operating demands, it outlines pathways ...
Hong Tang, Cui Ce, John Wang
wiley   +1 more source

Reconstructing Solvation Structure via Strongly Nucleophilic Anions for High‐Rate and Low‐Temperature Graphite||LFP Pouch Cells in PC‐Based Electrolyte

Advanced Energy Materials, EarlyView.
A nucleophilic‐anion‐regulated solvation strategy is developed for Propylene carbonate (PC)‐based electrolytes, where NO3−${\mathrm{NO}}_3^ - $ preferentially enters the Li+ solvation sheath and replaces coordinated PC molecules without sacrificing ionic conductivity.
Dichang Guan, Wenting Jia, Yue Fei, Zhiyuan Xue, Huan Ni, Guorong Hu, Zhongdong Peng, Yanbing Cao, Jian Wang, Qiang Liu, Ke Du, Ge Li   +11 more
wiley   +1 more source

Melatonin Enhances Thermal Resilience and Extends Worker Lifespan in Apis cerana via Redox–Metabolic Reprogramming

Insects
Apis cerana is widely managed in apiculture in Southern China but experiences substantial colony losses during prolonged summer heat. Developing effective strategies to support colony over-summering is therefore critical.
Ke Wang, Lianjun Zhou, Xianfu Xiang, Miaomiao Wei, Chenglian Lu, Wenfeng Li, Richou Han, Yi Zhang   +7 more
doaj   +1 more source

Evaluation and Ranking for Scientific, Transparent and Applicable of Chinese Geriatrics Guidelines and Consensus Published in 2023

AGING MEDICINE, EarlyView.
Evaluation of geriatric guidelines and consensus in 2023 using the STAR tool shows improved scientificity and transparency compared to 2022, though protocol development, funding, and clinical issues need refinement. Collaborative efforts among developers, journals, and experts are key to further elevating quality. ABSTRACT Objectives This study aims to
Daiping Li, Chao Gao, Xiaoli Huang, Ling Kang, Birong Dong, Jirong Yue, the Specialized Committee for Geriatric Medicine of the STAR, Daiping Li, Chao Gao, Xiaoli Huang, Ling Kang, Birong Dong, Jirong Yue   +12 more
wiley   +1 more source