Results 61 to 70 of about 395,280 (268)

Capping the CAP?

open access: yes, 2022
The income farmers receive from production fluctuates from year to year. The fragility of this income is why protectionist policies are implemented in developed countries, making agriculture on of the most distorted economic sectors. Protectionist policies secure a stable income for farmers but decrease the ability of other countries to compete on the ...
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Towards measuring political rents in agriculture: case studies of different agrarian structures in the EU

open access: yesAgricultural Economics (AGRICECON), 2018
It is generally believed that the subsidisation of agriculture serves as a payment of political rents to farmers. Here, we attempt to show that characterisation of the entire amount of subsidies as "political rent" is unjustified in the light of the ...
Bazyli CZYZEWSKI, Anna MATUSZCZAK
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Identification of Fatty Acids, Amides and Cinnamic Acid Derivatives in Supercritical-CO2 Extracts of Cinnamomum tamala Leaves Using UPLC-Q-TOF-MSE Combined with Chemometrics

open access: yesMolecules
Cinnamomum tamala leaf (CTL), also known as Indian bay leaf, is used all over the world for seasoning, flavoring, and medicinal purposes. These characteristics could be explained by the presence of several essential bioactive substances and lipid ...
Hema Lohani   +5 more
doaj   +1 more source

Price volatility of Polish agricultural commodities in the view of the Common Agricultural Policy

open access: yesAgricultural Economics (AGRICECON), 2018
In the paper, the price volatility was examined. The authors used 650 weekly observations from 2003 to 2015. Such a long period of analysis helped to reveal periods with high volatility.
Piotr BORAWSKI   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Effect of the domestic sectoral policies harmonisation in CECs with the EU Common Agricultural Policy

open access: yesAgricultural Economics (AGRICECON), 2003
This paper discusses the potential effects of the EU Common Agricultural Policy (CAP) on the various branches of the agricultural sector in the four OECD member Central European Countries (CECs), i.e.
V. Vojtěch
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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