Results 81 to 90 of about 2,514,420 (290)
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Portrait of Marie Darrieussecq as an altruistic animal lover
Truismes, de Marie Darriequssecq, ha dejado cierta inquietud en muchos de sus lectores. El tono perverso en el cual vemos la metamorfosis de una joven mujer en una cerda no puede ser tomado por un tratado sobre los derechos animales, sino parece ser ...
Annabelle Marie, Jean Louis Cornille
doaj
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
The Long-Term Effects of Poland’s Accession to the European Union: A Literature Review
The year 2024 marks 20 years since Poland joined the European Union. In this paper, the authors review the economic literature analysing the long-term economic effects of Poland’s membership in the EU.
Jan Jakub Michałek, Jan Hagemejer
doaj +1 more source
Common agricultural policy Health Check: the beginning of CAP’s re-nationalization?
The article analyses Common agricultural policy (CAP) Health Check (HC) negotiations process and outcome. It proposes realist, structural economic model, based on Moravcsik’s liberal intergovernmental theory, which has distinct conceptual and ...
Marko LOVEC, Emil ERJAVEC
doaj +1 more source
Bernstein-Gelfand-Gelfand sequences
This paper is devoted to the study of geometric structures modeled on homogeneous spaces G/P, where G is a real or complex semisimple Lie group and $P\subset G$ is a parabolic subgroup. We use methods from differential geometry and very elementary finite-
Cap, Andreas +2 more
core +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
https://newmedit.iamb.it/bup/wp-admin/post.php?post=95&action=edit
Organic farming is the most widespread alternative form of agriculture, widely applied all around the world. Within the last few decades, the cultivation of organic products presented a rising trend, due to consumer preferences for safe products ...
Christos Karelakis +3 more
doaj +1 more source

