Results 221 to 230 of about 3,906,604 (254)

The Drosophila HOAP protein is required for telomere capping

Nature Cell Biology, 2002
HOAP (HP1/ORC-associated protein) has recently been isolated from Drosophila melanogaster embryos as part of a cytoplasmic complex that contains heterochromatin protein 1 (HP1) and the origin recognition complex subunit 2 (ORC2). Here, we show that caravaggio, a mutation in the HOAP-encoding gene, causes extensive telomere-telomere fusions in larval ...
CENCI, GIOVANNI, SIRIACO G., RAFFA, GRAZIA DANIELA, KELLUM R., GATTI, MAURIZIO   +4 more
openaire   +4 more sources

Structural basis of mRNA cap recognition by proteins

Current Opinion in Structural Biology, 2000
Crystal structures have recently become available for two proteins (VP39 and eIF4E) complexed with their cognate ligand - the mRNA cap. Despite their total structural dissimilarity, both proteins bind N7-methylguanine between two parallel aromatic sidechains. The resulting stacked arrangement governs their high specificity for the alkylated form of the
F A, Quiocho, G, Hu, P D, Gershon
openaire   +2 more sources

Effect of capping protein on the kinetics of actin polymerization

Biochemistry, 1985
Acanthamoeba capping protein increased the rate of actin polymerization from monomers with and without calcium. In the absence of calcium, capping protein also increased the critical concentration for polymerization. Various models were evaluated for their ability to predict the effect of capping protein on kinetic curves for actin polymerization under
J A, Cooper, T D, Pollard
openaire   +2 more sources

Capping protein: new insights into mechanism and regulation

Trends in Biochemical Sciences, 2004
Temporal and spatial control of the actin cytoskeleton are crucial for a range of eukaryotic cellular processes. Capping protein (CP), a ubiquitous highly conserved heterodimer, tightly caps the barbed (fast-growing) end of the actin filament and is an important component in the assembly of various actin structures, including the dynamic branched ...
Martin A, Wear, John A, Cooper
openaire   +2 more sources

The Cap Structure of Eukaryotic Messenger RNA and its Interaction with Cap-binding Protein

1985
This article is a review of what is known about the 7-methylguanosine-containing “cap” structure of eukaryotic messenger RNA and its participation in the initiation of protein synthesis. Particular attention will be paid to the protein which is thought to mediate the entry of mRNA into the cycle of protein synthesis by recognizing the cap structure ...
openaire   +1 more source

Dynamic remodeling of actin networks by cyclase-associated protein and CAP-Abp1 complexes

Current Biology, 2023
Jeff Gelles, Bruce Goode, Siyang Guo
exaly  

The CAP superfamily protein PsCAP1 secreted by Phytophthora triggers immune responses in Nicotiana benthamiana through a leucine‐rich repeat receptor‐like protein

New Phytologist, 2023
Yuanchao Wang, Xi Chen, Wenwu Ye
exaly  

A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E

EMBO Journal, 2000
Josée Dostie, Nahum Sonenberg, Stephen Adam   +2 more
exaly  

Identification of the Cap-binding Protein of Two Strains of Influenza A/FPV

Journal of General Virology, 1982
Dieter Blaas, E Kuechler, Ernst Kuechler   +2 more
exaly  

Structure of a two-CAP-domain protein from the human hookworm parasiteNecator americanus

Acta Crystallographica Section D: Biological Crystallography, 2011
Oluwatoyin A Asojo
exaly