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A Unique Role of the Human Cytomegalovirus Small Capsid Protein in Capsid Assembly
mBio, 2022 Morphogenesis of herpesvirus particles is highly conserved; however, the capsid assembly and genome packaging of human cytomegalovirus (HCMV) exhibit unique features.
Eva Maria Borst +8 more
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Arthritogenic Alphavirus Capsid Protein
Life, 2021 In the past two decades Old World and arthritogenic alphavirus have been responsible for epidemics of polyarthritis, causing high morbidity and becoming a major public health concern. The multifunctional arthritogenic alphavirus capsid protein is crucial
Shambhavi Rao, Adam Taylor
doaj +5 more sources
The Alphaviral Capsid Protein Inhibits IRAK1-Dependent TLR Signaling
Viruses, 2021 Alphaviruses are arthropod-borne RNA viruses which can cause either mild to severe febrile arthritis which may persist for months, or encephalitis which can lead to death or lifelong cognitive impairments.
V. Douglas Landers +4 more
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Structure of the herpesvirus major capsid protein [PDF]
EMBO Journal, 2003 Herpes simplex virus-1 (HSV-1) virions are large, complex enveloped particles containing a proteinaceous tegument layer connected to an icosahedral capsid. The major capsid protein, VP5 (149 kDa), makes up both types of capsomere, pentons and hexons. Limited trypsin digestion of VP5 identified a single stable 65 kDa fragment which represents a proposed
Matthew Baker +2 more
exaly +3 more sources
L2, the minor capsid protein of papillomavirus
Virology, 2013 The capsid protein L2 plays major roles in both papillomavirus assembly and the infectious process. While L1 forms the majority of the capsid and can self-assemble into empty virus-like particles (VLPs), L2 is a minor capsid component and lacks the capacity to form VLPs. However, L2 co-assembles with L1 into VLPs, enhancing their assembly.
Richard Roden, Joshua W Wang
exaly +3 more sources
Stimulation of dendritic cell functional maturation by capsid protein from chikungunya virus [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): Chikungunya virus (ChikV) infection is characterized by persistent infection in joints and lymphoid organs. The ChikV Capsid protein plays an important role in regulating virus replication. In this study, we hypothesized that capsid protein
Vu Nghia +6 more
doaj +1 more source
IEEE Access, 2023 Capsid protein is a pathogenic protein that needs to be examined because it helps in the virus’s proliferation and mutation. Due to this protein, the virus can replicate and reproduce itself.
Anees Ur Rahman Khattak +6 more
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Capsid Proteins are Necessary for Replication of a Parvovirus [PDF]
Journal of Virology, 2020 A bstract Despite tight genetic compression, viral genomes are often organized in functional gene clusters, a modular structure that might favor their evolvability. This has greatly facilitated biotechnological developments, such as the recombinant Adeno-Associated
Labadie, Thomas +4 more
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Large-scale functional purification of recombinant HIV-1 capsid. [PDF]
PLoS ONE, 2013 During human immunodeficiency virus type-1 (HIV-1) virion maturation, capsid proteins undergo a major rearrangement to form a conical core that protects the viral nucleoprotein complexes.
Magdeleine Hung +7 more
doaj +1 more source
Vaccines, 2021 Porcine circovirus Type 2 (PCV2) is a primary etiological pathogen of post-weaning multi-systemic wasting syndrome (PMWS). The capsid protein of PCV2 is the crucial immunogenic protein which can induce antibody generation and immune responses.
Qingping Luo +6 more
doaj +1 more source