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The Astrovirus Capsid: A Review
Viruses, 2017 Astroviruses are enterically transmitted viruses that cause infections in mammalian and avian species. Astroviruses are nonenveloped, icosahedral viruses comprised of a capsid protein shell and a positive-sense, single-stranded RNA genome.
Carlos F. Arias, Rebecca M. DuBois
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Proton-Linked Dimerization of a Retroviral Capsid Protein Initiates Capsid Assembly [PDF]
Structure, 2009 In mature retroviral particles, the capsid protein (CA) forms a shell encasing the viral replication complex. Human immunodeficiency virus (HIV) CA dimerizes in solution, through its C-terminal domain (CTD), and this interaction is important for capsid assembly.
Bailey, Graham +3 more
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Ab initio modeling of the herpesvirus VP26 core domain assessed by CryoEM density [PDF]
, 2006 Efforts in structural biology have targeted the systematic determination of all protein structures through experimental determination or modeling.
Baker, David +23 more
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Capsid-Incorporation of Antigens into Adenovirus Capsid Proteins for a Vaccine Approach [PDF]
Molecular Pharmaceutics, 2010 Some viral vectors are potent inducers of cellular and humoral responses; therefore, viral vectors can be used to vaccinate against cancer or infectious diseases. This report will focus on adenovirus (Ad)-based vectors. Traditional viral-vector vaccination embodies the concept that the vector uses the host-cell machinery to express antigens that are ...
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, 2021 Upper left, threading model for PPV7/Col/Cundinamarca/2015 VP2-capsid protein obtained by ITASSER. Upper right, homology model for the PPV7/Col/Antioquia/2015 VP2-capsid protein elucidated with Modeler.
Dario Mogollón (11846809) +4 more
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Plant production and immunogenic characterisation of Human papillomavirus chimaeric vaccines [PDF]
, 2011 Includes abstract.Includes bibliographical references (leaves 153-175).Cervical cancer is primarily caused by infection with Human papillomavirus (HPV) and is a global concern, particularly in developing countries which contain ~80% of the cervical ...
Pineo, Catherine
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The effect of chemical chaperones on the assembly and stability of HIV-1 capsid protein. [PDF]
PLoS ONE, 2013 Chemical chaperones are small organic molecules which accumulate in a broad range of organisms in various tissues under different stress conditions and assist in the maintenance of a correct proteostasis under denaturating environments.
Ayala Lampel +4 more
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Characterisation of a non-pathogenic and non-protective infectious rabbit lagovirus related to RHDV [PDF]
, 2010 The existence of non-pathogenic RHDV strains was established when a non-lethal virus named rabbit calicivirus (RCV) was characterised in 1996 in Italy.
Le Gall-Reculé, Ghislaine +20 more
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Heat induced capsid disassembly and DNA release of bacteriophage λ. [PDF]
PLoS ONE, 2012 Successive structural changes of bacteriophage λ upon heating were characterized with quantitative experimental methods. In the commonly used Tris-Mg buffer, differential scanning calorimetry measurements first established that the protein capsid of λ ...
Xiangyun Qiu
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Molecular Therapy: Methods & Clinical Development, 2023 Recombinant adeno-associated viral vector (rAAV) mediated gene therapy is gaining traction in treating genetic disorders. Current rAAV production systems yield a mixture of capsids largely devoid of the transgene (empty capsid) compared with the desired ...
Ohnmar Khanal, Vijesh Kumar, Mi Jin
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