Results 51 to 60 of about 3,771,869 (289)
Diagnostic Potential of Parechovirus Capsid Proteins [PDF]
Journal of Clinical Microbiology, 2003 ABSTRACT To study humoral and cellular immunity against human parechovirus type 1 (HPEV1), the viral capsid proteins VP0, VP1, and VP3 were expressed and purified as glutathione S -transferase (GST)-tagged recombinant proteins. The fusion proteins were used to raise antisera in rabbits.
Annu, Alho +3 more
openaire +2 more sources
A kinase chaperones hepatitis B virus capsid assembly and captures capsid dynamics in vitro. [PDF]
PLoS Pathogens, 2011 The C-terminal domain (CTD) of Hepatitis B virus (HBV) core protein is involved in regulating multiple stages of the HBV lifecycle. CTD phosphorylation correlates with pregenomic-RNA encapsidation during capsid assembly, reverse transcription, and viral ...
Chao Chen +2 more
doaj +1 more source
PLoS Pathogens, 2020 Protein phosphorylation plays an important role during the life cycle of many viruses. Venezuelan equine encephalitis virus (VEEV) capsid protein has recently been shown to be phosphorylated at four residues.
Brian D Carey +9 more
doaj +1 more source
The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly [PDF]
The FEBS Journal, 2009 The mature capsid of human immunodeficiency virus, HIV‐1, is formed by the assembly of copies of a capsid protein (CA). The C‐terminal domain of CA, CTD, is able to homodimerize and most of the dimerization interface is formed by a single α‐helix from each monomer.
openaire +2 more sources
Assembly and Translocation of Papillomavirus Capsid Proteins [PDF]
Journal of Virology, 2002 ABSTRACT The major and minor capsid proteins of polyomavirus are preassembled in the cytoplasm and translocated to the nucleus only as a VP1-VP2/VP3 complex. In this study, we describe independent nuclear translocation of the L1 major protein and the L2 minor capsid protein of human papillomavirus type 33 by several approaches.
Luise, Florin +3 more
openaire +2 more sources
Computational validations of Colombian PPV7-VP2 capsid protein models.
, 2021 Computational validations of Colombian PPV7-VP2 capsid protein models.
Dario Mogollón (11846809) +4 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The capsid proteins of orthoflavivirus are interchangeable for West Nile virus assembly
Journal of VirologyOrthoflavivirus virions consist of an envelope enclosing a nucleocapsid core. A critical step in orthoflavivirus assembly is the encapsidation of genomic RNA by the capsid protein to form the nucleocapsid.
Jing Wang +4 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
The Hsv Ul17 Protein: Its Role In Capsid Assembly, Tegumentation, And Intranuclear Capsid Mobility [PDF]
, 2009 Employing a novel anti-pUL17 antibody I have resolved details of the physical relationship between the minor capsid protein, pUL17, and the herpes simplex virus (HSV-1) capsid and tegument layers.
Scholtes, Luella
core +5 more sources