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Arthritogenic Alphavirus Capsid Protein
In the past two decades Old World and arthritogenic alphavirus have been responsible for epidemics of polyarthritis, causing high morbidity and becoming a major public health concern. The multifunctional arthritogenic alphavirus capsid protein is crucial
Shambhavi Rao, Adam Taylor
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The Alphaviral Capsid Protein Inhibits IRAK1-Dependent TLR Signaling
Alphaviruses are arthropod-borne RNA viruses which can cause either mild to severe febrile arthritis which may persist for months, or encephalitis which can lead to death or lifelong cognitive impairments.
V. Douglas Landers +4 more
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Capsid protein is a pathogenic protein that needs to be examined because it helps in the virus’s proliferation and mutation. Due to this protein, the virus can replicate and reproduce itself.
Anees Ur Rahman Khattak +6 more
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A Unique Role of the Human Cytomegalovirus Small Capsid Protein in Capsid Assembly
Morphogenesis of herpesvirus particles is highly conserved; however, the capsid assembly and genome packaging of human cytomegalovirus (HCMV) exhibit unique features.
Eva Maria Borst +8 more
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Identification of Interactions between Sindbis Virus Capsid Protein and Cytoplasmic vRNA as Novel Virulence Determinants. [PDF]
Alphaviruses are arthropod-borne viruses that represent a significant threat to public health at a global level. While the formation of alphaviral nucleocapsid cores, consisting of cargo nucleic acid and the viral capsid protein, is an essential ...
Kevin J Sokoloski +6 more
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Structures of Three Actinobacteriophage Capsids: Roles of Symmetry and Accessory Proteins
Here, we describe the structure of three actinobacteriophage capsids that infect Mycobacterium smegmatis. The capsid structures were resolved to approximately six angstroms, which allowed confirmation that each bacteriophage uses the HK97-fold to form ...
Jennifer Podgorski +6 more
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Human Cytomegalovirus Capsid Assembly Protein Precursor (pAP, UL80.5) plays a key role in capsid assembly by forming an internal protein scaffold with Major Capsid Protein (MCP, UL86) and other capsid subunits.
Zhigang Zhang +5 more
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RNA packaging and uncoating in simple single-stranded RNA viruses [PDF]
Simple (non-enveloped) small, positive-sense single-stranded RNA viruses infect hosts from all kingdoms of life. However, their assembly and uncoating processes remain poorly understood. For turnip crinkle virus (TCV), 3D reconstructions by cryoelectron
Bakker, Saskia
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Capsid Proteins are Necessary for Replication of a Parvovirus [PDF]
A bstract Despite tight genetic compression, viral genomes are often organized in functional gene clusters, a modular structure that might favor their evolvability. This has greatly facilitated biotechnological developments, such as the recombinant Adeno-Associated
Labadie, Thomas +4 more
openaire +5 more sources
Stimulation of dendritic cell functional maturation by capsid protein from chikungunya virus [PDF]
Objective(s): Chikungunya virus (ChikV) infection is characterized by persistent infection in joints and lymphoid organs. The ChikV Capsid protein plays an important role in regulating virus replication. In this study, we hypothesized that capsid protein
Vu Nghia +6 more
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