Results 101 to 110 of about 3,331,817 (302)

The role of community integration and empowerment for the transformative change in community mental health

open access: yesCommunity Psychology in Global Perspective, 2019
The present article first presents a critique about the current status of the CMH field; and second based in theoretical and empirical literature it presents a perspective inspired by the inception of community psychology, namely the empowerment and ...
José Ornelas   +3 more
doaj  

Complexity synchronization in emergent intelligence

open access: yesScientific Reports
In this work, we use a simple multi-agent-based-model (MABM) of a social network, implementing selfish algorithm (SA) agents, to create an adaptive environment and show, using a modified diffusion entropy analysis (DEA), that the mutual-adaptive ...
Korosh Mahmoodi   +5 more
doaj   +1 more source

PRIMDEx: Prototyping rapid innovation of microfluidics devices for experimentation

open access: yesSLAS Technology
Microfluidics has quickly become an established technology in the transformative fields that make up broader biotechnology. Microfluidics has applications spanning the entire breadth of the discipline, from chemical synthesis, environmental monitoring ...
Patrick B. Kruk, Jose A. Wippold
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Developing people capabilities for the promotion of sustainability in facility management practices [PDF]

open access: yes, 2015
Sustainability is becoming an integral part of the life-cycle development of built facilities. It is increasingly highlighted during the post construction phase, as facility management personnel can have major influence to the sustainability agenda
Sarpin, Norliana
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A GPU-Implemented Lattice Boltzmann Model for Large Eddy Simulation of Turbulent Flows in and around Forest Shelterbelts

open access: yesAtmosphere
Using porous wind barriers for the microclimate modification of agricultural lands, urban areas, and surrounding roads is a ubiquitous practice. This study establishes a new method for numerically modeling the turbulent flow in and around forest ...
Yansen Wang   +3 more
doaj   +1 more source

DRIVING TRANSFORMATION FROM THE TOP: DISTELL’S JOURNEY TO END-TO-END SUPPLY CHAIN EXCELLENCE

open access: yesSouth African Journal of Industrial Engineering, 2019
Distell Group (a listed South African alcoholic beverage company) embarked on a business improvement journey that required a significant change to its supply chain structure and capability, which were inadequate to meet its 2020 strategic ambitions, to ...
Petrarolo, Dino , Everson, Cecil
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Change, Coordination, and Capabilities [PDF]

open access: yes
Empirical studies on coordination of economic activities focused on the two polar cases of governance mode, namely vertical integration and market exchanges. Whether firms should be vertically integrated or lever market exchanges in the face of change is,
Andrea Prencipe
core  

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