Results 201 to 210 of about 4,295,333 (324)

Addressing Reproducibility Challenges in High-Throughput Photochemistry

JACS Au
Brenda Pijper, Lucía M. Saavedra, Matteo Lanzi, Maialen Alonso, Alberto Fontana, Marta Serrano, José Enrique Gómez, Arjan W. Kleij, Jesús Alcázar, Santiago Cañellas   +9 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Empowering People With Haemophilia: A Mobile Solution for Self-Management. [PDF]

Healthc Technol Lett
Azizi Alavijeh A, Moulaei K, Ghaemi MM, Bahaadinbeigy K.   +3 more
europepmc   +1 more source

Big data analytics and firm performance: Effects of dynamic capabilities

, 2017
S. Wamba, A. Gunasekaran, Shahriar Akter, S. Ren, Rameshwar Dubey, S. Childe   +5 more
semanticscholar   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Evaluation of the Diagnostic Capabilities of Artificial Intelligence (GPT-4) in a Cardiology Department in Sub-Saharan Africa: Cross-Sectional Study. [PDF]

Health Sci Rep
Nacanabo MW, Seghda AAT, Tall/Thiam A, Millogo GCR, Bayala YLT, Yameogo VN, Samadoulougou AK, Zabsonre P.   +7 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

AI-Powered Service Robots for Smart Airport Operations: Real-World Implementation and Performance Analysis in Passenger Flow Management. [PDF]

Sensors (Basel)
Giannopoulou E, Demestichas P, Katrakazas P, Saliverou S, Papagiannopoulos N.   +4 more
europepmc   +1 more source

Augmenting mobile phone capabilities by adaptive offloading [PDF]

, 2011
Verbelen, Tim
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source