Results 101 to 110 of about 1,404,975 (316)

A critical review of the capability approach in Australian Indigenous policy [PDF]

open access: yes, 2015
The capability approach has recently been used in Australian Indigenous policy formation. Of particular note is how it has been used in some instances to justify current paternalistic and directive policies for Indigenous Australians.
Elise Klein, Klein, Elise
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Capability Design with CDD

open access: yes, 2018
One of the key tasks of the CDD methodology concerns designing capabilities starting from existing business requirements, enterprise models, and other kinds of organizational designs.
Valverde, Francsico   +7 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Education, Work, and Motherhood in Low and Middle Income Countries: A Review of Equality Challenges and Opportunities for Women with Disabilities

open access: yesSocial Inclusion, 2018
This study looks at the equality challenges and opportunities for women with disabilities in low and middle income countries (LMICs) to participate and succeed in education, employment and motherhood.
Belaynesh Tefera   +5 more
doaj   +1 more source

Commensurable freedoms in the capability approach [PDF]

open access: yes
The basis of the capability approach (CA) was recently attacked by a paper by Prasanta Pattanaik and Yonghseng Xu: the CA is strongly committed to two substantial principles, dominance on the one hand, and relativism on the other hand.
Antoinette Baujard
core  

Building institutional capability in e-learning design [PDF]

open access: yes, 2008
We detail the research, development and initial outcomes of an intervention process to promote capability building in designing for e‐learning at a dual mode university in the UK.
Armellini, Alejandro   +6 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

A knowledge management framework to grow innovation capability maturity

open access: yesSouth African Journal of Information Management, 2012
Background: Innovation is a key prerequisite for being organisationally competitive. Therefore, it is imperative that enterprises grow and mature their innovation capability.
Denéle Esterhuizen   +2 more
doaj  

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