Results 81 to 90 of about 895,061 (267)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

An empirical analysis of asset misappropriation fraud during the COVID-19 crisis [PDF]

open access: yesProblems and Perspectives in Management
The objective of this paper is to examine asset misappropriation fraud during the COVID-19 pandemic. The study examines the impact of four elements of fraud risk factors and Islamic religiosity on the propensity for fraud among employees who manage ...
Darsono Darsono   +4 more
doaj   +1 more source

Groups and Capabilities

open access: yesJournal of Human Development, 2005
The paper suggests that groups should be given a more central role than they generally are in the capability approach. Being a member of a group or groups is an intrinsic aspect of human life: the quality of groups with which individuals identify forms an important direct contribution to their well-being, is instrumental to other capabilities, and ...
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The European skill space: a cross-country analysis of path-dependent capability development

open access: yesBaltic Journal of Economics
This study investigates the skill structures of European countries and their transformations from the perspective of capability development. The constructed skill space illustrates the skill sets of European nations based on product space methodology by ...
Sonja Walter, Wonsub Eum, Jeong-Dong Lee
doaj   +1 more source

Capability passing processes

open access: yesScience of Computer Programming, 2006
AbstractCapability-passing processes model global applications in a way that decouples the global agreement aspects of protocols from the details of how the communications are actually made. It relies on a restricted API or programming language and on the exchange of digital certificates representing capabilities to ensure that participants are ...
T. Chothia (Tom), D. Duggan
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Assessing the success of a research leadership programme for senior nurses and midwives: A mixed methods programme evaluation

open access: yesNursing Open
Aims In 2018 the National Institute of Health and Care Research, United Kingdom, launched a 3‐year Senior Nurse and Midwife Research Leader Programme to support nurse and midwifery research leaders to develop research capacity and capability within NHS ...
Julie Christine Menzies   +2 more
doaj   +1 more source

Impact the IT Capability on Business Agility [PDF]

open access: yesمطالعات مدیریت کسب و کار هوشمند, 2014
activities and corporate structures are presented in 21 century. Business Agilityalongside other theories in the management of the company's success in theturbulent market environment is essential.
Mohammad Bashokouh, Mitra Shekasteband
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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