Results 61 to 70 of about 638,237 (304)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

THE EXPERIENCES OF CHILDREN WITH DISABILITIES AND PRIMARY CAREGIVERS ON THE SOCIAL INCLUSION OF CHILDREN WITH DISABILITIES IN ETHIOPIA

open access: yesInternational Journal of Child, Youth & Family Studies, 2018
This article presents the findings of a qualitative study on the social inclusion of children with disabilities in Addis Ababa, Ethiopia and how this affects their achievement of valued life goals.
Belaynesh Tefera   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Chapter Platform Workers, Autonomy, and the Capability Approach

open access: yes
In this short essay dedicated to the memory of Riccardo Del Punta, my aim is to highlight one of his (many) contributions to labour law, and to reflect on possible ways to apply it on a timely question.
Davidov, Guy
core   +1 more source

Capabilities expansion for marginalised migrant youths in Johannesburg: The case of Albert Street School

open access: yesHTS Teologiese Studies/Theological Studies, 2018
In this article, we used the capability approach as normative grounding to analyse a particular faith-based intervention targeting ‘youth at the margins’ – in this instance, marginalised migrant youths from Zimbabwe living in Johannesburg, South Africa ...
Wadzanai F. Mkwananzi   +1 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Capability Approach and computational thinking as strategy: survey on a sample of primary school teachers

open access: yes, 2022
reservedAbstract: Questo studio riguarda la relazione tra pensiero computazionale e l’insegnamento della matematica nella scuola primaria. Il framework teorico si basa sul Capability Approach.
ROSSI, ANGELA
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Philosophy With Feet in the Mud

open access: yesErasmus Journal for Philosophy and Economics, 2018
The Erasmus Journal for Philosophy and Economics interviewed Professor Robeyns about her formative years, her scholarship on the capability approach, her ERC-funded Fair Limits project, the relevance of political philosophy for public policy, and her ...
Ingrid Robeyns
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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