Results 61 to 70 of about 333,390 (298)

Anisotropic Anomalous Diffusion assessed in the human brain by scalar invariant indices

, 2010
A new method to investigate anomalous diffusion in human brain is proposed. The method has been inspired by both the stretched-exponential model proposed by Hall and Barrick (HB) and DTI.
Bozzali, M., Capuani, S., De Santis, S., Gabrielli, A., Macaluso, E., Maraviglia, B.   +5 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Housing and quality of life for migrant communities in western Europe: a capabilities approach [PDF]

, 2013
Housing is an important determinant of quality of life and migrants are more likely to encounter poor quality housing than natives. This paper draws on the capabilities approach to welfare economics to examine how issues of housing and neighborhood ...
Anand, Paul, Coates, Dermot, Norris, Michelle   +2 more
core   +2 more sources

Process Yield and Capability Indices [PDF]

Communications in Statistics - Theory and Methods, 2011
Capability indices were introduced to allow comparing the performance of various processes independently of their tolerance interval. The concept of performance, related first to the proportion of conforming items (process yield), quickly evolved to also take into account the process position compared to its target (process centering).
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Design of methodology for application of statistical control on short run processes in metallurgy

Metalurgija, 2014
So called short run manufacturing environment is now typical for many industrial branches including metallurgy. To be applicable in such nonstandard conditions classical control charts and capability indices must be modified.
D. Noskievičová, B. Woska
doaj  

Power system security enhancement by HVDC links using a closed-loop emergency control [PDF]

, 2019
In recent years, guaranteeing that large-scale interconnected systems operate safely, stably and economically has become a major and emergency issue.
Allaoui, Tayeb, Benasla, Mokhtar, Brahami, Mostefa, Denai, Mouloud, Sood, Vijay   +4 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Estimation and Confidence Intervals of a New PCI CNpmc for Logistic-Exponential Process Distribution

Journal of Mathematics, 2022
The process capability index has been introduced as an effective tool used in industries to aid in the assessment of process performance as well as to measure how much the product meets the costumer expectations.
Refah Alotaibi, Sanku Dey, Mahendra Saha
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source