Results 71 to 80 of about 204,415 (295)

PSP Performance Analysis Report [PDF]

open access: yes, 2011
The Personal Software Process (PSP) is a structured software development process that is intended to help software engineers understand and improve their performance, by using a disciplined, data-driven procedure.
Ivanova, Valentina
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Bridging the Capability Gap: A Multidimensional Maturity Model for Smart City Development in German Municipalities

open access: yesUrban Science
Municipal smart city programs remain hampered by conceptual fragmentation and the absence of validated, context-specific maturity assessments. We develop the Smart Municipality Maturity Model (SMMM) via a design-science process, synthesizing 183 ...
Bernhard Koelmel   +3 more
doaj   +1 more source

Higher capability maturity dynamics of UK construction organisations [PDF]

open access: yes
This paper attempts to identify the dynamics of the CMM (Capability Maturity Model) higher capability maturity level characteristics within the UK construction context from a theoretical perspective.
Amaratunga, Dilanthi   +2 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Identifying higher capability maturity KPAs of construction organisations; Model refinement through expert interviews [PDF]

open access: yes
Process improvement has been identified as a mechanism of achieving the much needed performance improvements within the construction industry. Despite the concerns of being an industry with unique characteristics, construction has borrowed some process ...
Amaratunga, Dilanthi   +2 more
core  

owards Mature Measurement Programs [PDF]

open access: yes, 1998
Many organizations are using measurement as a means to improve their software development and maintenance processes. A reasonable consensus has been reached about the main success factors for measurement programs.
Niessink, F., Vliet, H. van
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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