Results 221 to 230 of about 1,559,477 (277)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Relationships Between Dry-Land Load-Velocity Parameters and In-Water Bioenergetic Performance in Competitive Swimmers. [PDF]

Sports (Basel)
Amara S, Bouassida A, Tillaar RVD.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Attachment Classification, Emotion Regulation, and Defense Mechanisms: An Integrative Narrative Review. [PDF]

Healthcare (Basel)
Morris AM, Freeberg-Powell E, Verma S, Di Giuseppe M, Crespo H, Hoffman L, Rice T.   +6 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Piloting a framework to explore the impacts of public health workforce capacity-building initiatives. [PDF]

Front Public Health
Frost C, Lawless JW, Leong D, Meredith GR.   +3 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Solar-driven oil spill recovery using a carbon dots/loofah sponge. [PDF]

RSC Adv
Hau LT, Thu Thuy T, Ngoc NTB, Nguyen V, Hong Ha VT, Hung VN, Choi HS, Ho NX, Dieu Linh D, Dao VD.   +9 more
europepmc   +1 more source

Role of anthropogenic mineral circularity in addressing dual challenges of resource supply and waste management in global photovoltaic development. [PDF]

Nat Commun
Yuan X, Song Q, Liu Y, Huang M, Wang Y, Xu Z.   +5 more
europepmc   +1 more source

Cutting-Edge Research on Physical Fitness Profile in Soccer Players. [PDF]

Sports (Basel)
Michailidis Y.
europepmc   +1 more source