Results 61 to 70 of about 361,420 (264)

We Grew Up on Shoulders of Our Predecessors: on Anniversary of Alexander I. Krupnov

open access: yesRUDN Journal of Psychology and Pedagogics, 2019
The article is dedicated to the 80th anniversary of the birth of Dr. habil. in Psychology, Professor A.I. Krupnov. It analyzes the continuity and achievements of scientific research on differential psychology in Russian science. Advantages of A.I.
Alexey K. Osnitsky
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Here comes the water: Risk assessments, observation and knowledge of Ompundja village

open access: yesJàmbá, 2019
Floods in Namibia are more pronounced than drought or any other natural disaster. Ompundja village in northern central Namibia has experienced severe flooding over the last decade since the village is a catchment area of water from two distinct sources ...
Loide Shaamhula, Gert van Rooy
doaj   +1 more source

Capacities and Games on Lattices: A Survey of Result [PDF]

open access: yes
We provide a survey of recent developments about capacities (or fuzzy measures) and ccoperative games in characteristic form, when they are defined on more general structures than the usual power set of the universal set, namely lattices. In a first part,
Michel Grabisch
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Regular updating [PDF]

open access: yes
We study the Full Bayesian Updating rule for convex capacities. Following a route suggested by Jaffray (1992), we define some properties one may want to impose on the updating process, and identify the classes of (convex and strictly positive) capacities
Thibault Gajdos   +2 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

K-balanced games and capacities [PDF]

open access: yes
In this paper, we present a generalization of the concept of balanced game for finite games. Balanced games are those having a nonempty core, and this core is usually considered as the solution of game.
Michel Grabisch, Pedro Miranda
core  

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