Results 61 to 70 of about 4,405,974 (289)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A Single Phase, Single Stage AC-DC Multilevel LLC Resonant Converter With Power Factor Correction
IEEE Access, 2021 Single stage LLC resonant converters with inherent power factor correction are getting popularity in AC-DC converters due to its reduced size and weight.
Antony K. Peter, Jaison Mathew
doaj +1 more source
Família de retificadores PWM unidirecionais três-níveis híbridos a capacitor chaveado com elevado fator de potência [PDF]
, 2015 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2015.Esta tese de doutorado tem por objetivo a proposta de uma nova família de conversores ca-cc três níveis ...
Cortez, Daniel Flores
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Seven-level inverter with switched capacitors
The Journal of Engineering, 2019 The seven-level (7L) inverter with a nearly sinusoidal output voltage is suitable for renewable energy conversion applications. A novel 7L inverter topology with switched capacitors is proposed here.
Xuezhi Wu +5 more
doaj +1 more source
A High Step-up Integrated Coupled Inductor-Capacitor DC-DC Converter
IEEE Access, 2021 A high step-up integrated coupled inductor-capacitor DC-DC converter for renewable energy applications has been proposed in this paper. Because of relative low output voltage of renewable energy systems, a high step-up converter is necessary.
Raheel Afzal +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
A DC Capacitor-Less Two-Terminal Unified Active Capacitor and Inductor
2022 IEEE Applied Power Electronics Conference and Exposition (APEC), 2022 Flexible characteristics, tunable parameters, and improved power density are the desired attributes that have led to widespread research on active capacitors and inductors (ACI) in power conversion systems. However, the two-terminal realisation of ACI is challenging due to different trade-offs between power density, device stress, and reliability of ...
Anwesha Mukhopadhyay +2 more
openaire +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source