Results 171 to 180 of about 26,945 (306)

Targeting the noncatalytic activity of GSK3β modulates neuronal excitability in medium spiny neurons via Nav1.6 interactions

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Kinases phosphorylate ion channels, but their noncatalytic roles via protein–protein interactions (PPI) are less understood. Here, we identified the peptidomimetic ZL141 to characterize the PPI between GSK3β and Nav1.6, revealing a noncatalytic role for GSK3β in regulating Nav1.6 currents and neuronal excitability ...
Aditya K. Singh, Zahra Haghighijoo, Akanksha Gurtu, Nolan M. Dvorak, Timothy J. Baumgartner, Nana A. Goode, Jully Singh, Matteo Bernabucci, Adam T. Szafran, Michael J. Bolt, Michael A. Mancini, Natalie M. Dvorak, Marijn Lijffijt, Zhiqing Liu, Yu Xue, Alyssa K. Thomas, Alejandro Villasante‐Tezanos, Balaji Krishnan, Jia Zhou, Fernanda Laezza   +19 more
wiley   +1 more source

Using copper-foil explosions to generate underwater focusing shocks of different geometries. [PDF]

Exp Fluids
Rojas Mata S, Hernández Garcia F, Liverts M.   +2 more
europepmc   +1 more source

A hybrid pelican-GWO optimized fractional order PID controller for enhanced performance of hybrid active power filters. [PDF]

Sci Rep
Salah Eldeen RS, Elkoshairy AD, Mageed HMA, Ahmed AAEMS.   +3 more
europepmc   +1 more source

Accountability and Hyperaccountability in Child Protection Scandals

Child &Family Social Work, EarlyView.
ABSTRACT The number of child abuse–related deaths has decreased significantly in the United Kingdom over the past 50 years, but there remains public and political concern about the actual and perceived risk of child deaths, with resultant processes enacted to supervise child protection practice.
Robin Sen, John Devaney
wiley   +1 more source

Transmission line fault detection and classification using bi-orthogonal wavelet transform (5.5) based signal decomposition. [PDF]

Sci Rep
Chothani N, Sheikh M, Patel D, Singh S, Varshney D, Chan CK, Sonawane C, Bongale A.   +7 more
europepmc   +1 more source

‘We Live in Different Worlds, But We Try to Connect’—Parents' Perceptions of Parenting Experiences With Children With Autism Spectrum Disorder: A Qualitative Study

Child &Family Social Work, EarlyView.
ABSTRACT While a great deal of research has been conducted to investigate the parenting experiences of parents with autistic children, much of this research focuses on Western societies; very little is known about the everyday difficulties of and the strategies adopted in raising an autistic child in China, where the prevalence of autism is increasing.
Xue‐Ke Song, Xin Zhang, Yu Meng, Sai‐Yuan Zheng, Wing‐Chee So   +4 more
wiley   +1 more source

Energy storage-enabled fractional-order virtual synchronous generator for DC-link voltage regulation in DC microgrid under load and renewable disturbances. [PDF]

Sci Rep
Bakeer A, Hussain S, Chub A, Salama HS, Magdy G.   +4 more
europepmc   +1 more source

SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis

Cell Proliferation, EarlyView.
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu, Wenfeng Zhang, Xiao Jiang, Jianping Chen, Lei Zhu, Zhonghao Zhang, Jing Gu, Lulu Guo, Lin Ao, Qing Chen, Lei Sun, Yuhan Hu, Xin Wang, Yaxin Liu, Jia Cao, Fei Han, Jinyi Liu   +16 more
wiley   +1 more source

Design and control of LCC DVR. [PDF]

Sci Rep
Manju AS, Manitha PV, Nair MG, Joseph A.
europepmc   +1 more source

Technical Quality and Students' Perception of Endodontic Preclinical Training Using Natural or LikeReal Artificial Teeth

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction This study evaluated and compared the technical quality of treatments performed during the preclinical training using artificial and natural teeth and the students' perceptions regarding their learning process with the 2 groups. Materials and Methods The study assessed the teeth used for preclinical training by 2nd‐year students ...
Gabriela Biagioni, Fernanda Comodo, Marcelo Santos Coelho   +2 more
wiley   +1 more source