Results 121 to 130 of about 8,341 (195)

Cancer‐Associated Fibroblasts Promote Tumor Immunosuppression in Hepatocellular Carcinoma via the NNMT‐ANGPTL4 Axis

Advanced Science, EarlyView.
ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu, Shanjia Ke, Hongjun Yu, Zhanzhi Meng, Miaoyu Bai, Yanan Xu, Hui Zhu, Jinwen Yang, Baolin Qian, Bing Yin, Chaoqun Wang, Zhigang Feng, Zhongyu Li, Yongzhi Zhou, Zihao Li, Xinglong Li, Yongliang Hua, Yao Fu, Wei Tang, Yaohua Wu, Yong Ma   +20 more
wiley   +1 more source

Feedback Approach for the Relay Channel with Noisy Feedback and Its Security Analysis. [PDF]

Entropy (Basel)
Hu R, Zhang H, Yang H.
europepmc   +1 more source

Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu, Haihong Lai, Qing Yang, Chaoyue Zhang, Bin Jia, Qiyi Chen, Yuling Deng, Fen Cao, Yuyu You, Zhe Li, Dongming Kuang, Bo Li   +11 more
wiley   +1 more source

Unique Information Through the Lens of Channel Ordering: An Introduction and Review. [PDF]

Entropy (Basel)
Banerjee PK.
europepmc   +1 more source

The Secret Key Capacity of a Class of Noisy Channels with Correlated Sources. [PDF]

Entropy (Basel), 2019
Bassi G, Piantanida P, Shamai Shitz S.
europepmc   +1 more source

A Persistent Homology-Based Topological Loss for CNN-Based Multiclass Segmentation of CMR. [PDF]

IEEE Trans Med Imaging, 2023
Byrne N, Clough JR, Valverde I, Montana G, King AP.   +4 more
europepmc   +1 more source

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source

Do corals dream of simulated seas? [PDF]

Hist Philos Life Sci
Bright D.
europepmc   +1 more source

Cholinergic shaping of neural correlations. [PDF]

Proc Natl Acad Sci U S A, 2017
Minces V, Pinto L, Dan Y, Chiba AA.
europepmc   +1 more source

The Postdigital University: Do We Still Need Just a Little of That Human Touch? [PDF]

Postdigit Sci Educ, 2021
Cureton D, Jones J, Hughes J.
europepmc   +1 more source