Results 91 to 100 of about 9,802,175 (300)

Challenges and opportunities for greater public-private partnership for the implementation of the WHO operational framework for building climate resilient health systems to improve malaria control and elimination in Sub-Saharan Africa: a rapid review

open access: yesFrontiers in Health Services
The relationship between climate change and malaria is complex, with both predictable and unpredictable aspects. The impacts of climate change may promote mosquito breeding, increase parasite development rates and extend the geographical range of malaria
Sheila Lumumba   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Newsletter analytical and capacity development partnership (ACDP), June 2015 [PDF]

open access: yes, 2015
The newsletter ACDP have information about development of quality assurance system for early childhood education, overview of the Islamic education sub-sector in Indonesia, improving teacher workforce planning in Aceh, and evaluation of ict in education ...
Analytical and Capacity Developmentfd Partnership (ACDP) Indones, Analytical and Capacity Developmentfd Partnership (ACDP) Indones
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Capacity Bounded Grammars and Petri Nets

open access: yes, 2009
A capacity bounded grammar is a grammar whose derivations are restricted by assigning a bound to the number of every nonterminal symbol in the sentential forms.
Bianca Truthe   +13 more
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Correlative Capacity of Composite Quantum States

open access: yes, 2009
We characterize the optimal correlative capacity of entangled, separable, and classically correlated states. Introducing the notions of the infimum and supremum within majorization theory, we construct the least disordered separable state compatible with
A. Marshall   +4 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Bridging the bioinformatics gap: tool selection for decentralized AMR genomic surveillance in Africa

open access: yesFrontiers in Public Health
Antimicrobial resistance (AMR) poses a significant threat to public health, particularly in low- and middle-income countries where centralized genomic surveillance infrastructure is limited.
Niamh Lacy-Roberts   +6 more
doaj   +1 more source

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