Results 111 to 120 of about 4,646,161 (317)

Early Grade Literacy in Latin America and the Caribbean: Jamaica Stakeholder Mapping and Analysis

open access: yes, 2019
The LAC Reads Capacity Program (LRCP) aims to increase the impact, scale, and sustainability of early grade literacy (EGL) activities in priority countries in Latin America and the Caribbean (Jamaica, Haiti, Dominican Republic, Guatemala, Honduras ...
USAID/LAC Reads Capacity Program
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Optimization of nanopore sequencing for surveillance of antimicrobial resistance in low-resource settings

open access: yesFrontiers in Public Health
Whole-genome sequencing (WGS) is emerging as a valuable tool for antimicrobial resistance (AMR) surveillance, yet implementation in low-resource settings remains limited by prohibitory costs and infrastructure constraints.
Natasia R. Thornval   +7 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

our capacity for capacity [PDF]

open access: yesChemical & Engineering News Archive, 1968
openaire   +3 more sources

Capacity And Capacity Utilization In Fishing Industries

open access: yes, 2003
The definition and measurement of capacity in fishing and other natural resource industries possess unique problems because of the stock-flow production technology, in which inputs are applied to the natural resource stock to produce a flow of output. In
Squires, Dale, Kirkley, James E.
core  

High capacity and long-haul transmission with space-division multiplexing

open access: yes, 2021
We report on recent wideband, high-capacity transmission experiments using either few-mode or coupled-core multi-core fibers. We show that the coupled-core multi-core fiber has overall favorable transmission properties at the cost of a lower spatial ...
Essiambre, René Jean   +10 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Dual Clinical Practice (DCP) policy to improve the retention of human resources for health in Rwanda: a mid-term review using a cross-sectional and retrospective study design

open access: yesBMC Health Services Research
Background Despite the high demand for public services globally, ensuring the quality of services provided by public health facilities is challenging.
Kizito Kayumba   +14 more
doaj   +1 more source

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