Results 161 to 170 of about 12,966,863 (379)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Common criteria for evaluating cross-disciplinary research in global health: a scoping review

open access: yesBMC Global and Public Health
Background Solutions to global health challenges depend on nations’ capacity for cross-disciplinary research in global health. Despite longstanding demands for practical guidelines, published guidance and frameworks for evaluating cross-disciplinary ...
Yan Ding   +3 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Relational trust in outreach with women experiencing street-involvement in British Columbia, Canada: a qualitative study

open access: yesBMC Health Services Research
Background Women who experience street-involvement are severely underserved in health care. Outreach can address this service gap, but little is known about what constitutes gender-appropriate and effective outreach worker-client relationships in this ...
Michelle Gagnon   +5 more
doaj   +1 more source

GRIDCERF: Geospatial Raster Input Data for Capacity Expansion Regional Feasibility

open access: green, 2023
Chris Vernon   +3 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

our capacity for capacity [PDF]

open access: yesChemical & Engineering News Archive, 1968
openaire   +3 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy