Results 41 to 50 of about 10,079,690 (327)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Data-Driven Projections Demonstrate Non-Farming Use of Cropland in Non-Major Grain-Producing Areas: A Case Study of Shaanxi Province, China

Agronomy, 2023
The non-farming use of cropland has led to food insecurity in China due to drastic land use (LU) changes under the stresses of ecological restoration and urbanization, particularly in non-major grain-producing areas.
Linna Linghu, Peijun Sun, Meng Zhang, Yue Wu   +3 more
doaj   +1 more source

Embedding mutually supportive implementation of the Plant Treaty and the Nagoya Protocol in the context of broader national policy goals: A Workshop for National Teams of Policy Actors, 16th – 20th November 2015 [PDF]

, 2016
This report provides highlights from a workshop entitled “Embedding mutually supportive implementation of the Plant Treaty and the Nagoya Protocol in the context of broader national policy goals. A workshop for national teams of policy actors”.
ABS Capacity Development Initiative, Bioversity International   +1 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

HIV viral load suppression and associated factors among PLHIV with non-communicable diseases in Uganda’s Teso Region: a cross-sectional retrospective study

AIDS Research and Therapy
Background As Uganda scales up integrated chronic care, understanding viral load suppression (VLS) among people living with HIV (PLHIV) with non-communicable diseases (NCDs) is critical for optimizing service delivery.
Bonniface Oryokot, Saadick Mugerwa Ssentongo, Abraham Ignatius Oluka, Timothy Otaala, Halima Sairo, Abel Muniina, Denis Jacob Olweny, Baker Bakashaba, Antonio Rodriguez Andres   +8 more
doaj   +1 more source

Dolutegravir use over 48 weeks is not associated with worsening insulin resistance and pancreatic beta cell function in a cohort of HIV-infected Ugandan adults

AIDS Research and Therapy, 2023
Background The Uganda Ministry of Health issued restrictive guidelines on the use of dolutegravir (DTG) in persons stratified to have a heightened risk of diabetes mellitus.
Frank Mulindwa, Barbara Castelnuovo, Nele Brusselaers, Martin Nabwana, Robert Bollinger, Allan Buzibye, Eva Laker Agnes Odongpiny, Ronald Kiguba, Jean-Marc Schwarz   +8 more
doaj   +1 more source

Imbrication de la mise en oeuvre concertée et solidaire du Traité sur les ressources phytogénétiques et du Protocole de Nagoya dans le conexte d’objetifs de politiques nationales plus larges: un atelier destine à des équipes nationales d’acteurs de politiques [PDF]

, 2019
This report provides highlights from a workshop entitled “Embedding mutually supportive implementation of the Plant Treaty and the Nagoya Protocol in the context of broader national policy goals. A workshop for national teams of policy actors”.
ABS Capacity Development Initiative, Bioversity International   +1 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Spatiotemporal Variability in the Glacier Snowline Altitude across High Mountain Asia and Potential Driving Factors

Remote Sensing, 2021
The glacier snowline altitude (SLA) at the end of the melt season is an indicator of the glacier equilibrium line altitude and can be used to estimate glacier mass balance and reconstruct past climate.
Zhongming Guo, Lei Geng, Baoshou Shen, Yuwei Wu, Anan Chen, Ninglian Wang   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source