Results 141 to 150 of about 461,686 (258)

Capacity building for genomic surveillance of mpox and other emerging diseases in resource-limited settings within the African Great Lakes region. [PDF]

Commun Med (Lond)
Schuele L, Nzoyikorera N, Udahemuka JC, Cassidy H, Murhula Masirika L, Nieuwenhuijse DF, Nduwimana C, Molenkamp R, Nyandwi J, Boter M, Minega Ndoli J, Zaeck LM, Musabyimana JP, de Vries RD, Mbiribindi JB, Siangoli FB, Otani S, Aarestrup FM, Koopmans M, Ndishimye P, Oude Munnink BB.   +20 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Medical Technology Transfer and Health System Capacity Building in Pakistan: Evidence from the China-Pakistan Economic Corridor. [PDF]

Pak J Med Sci
Tong Z, Qiumei Q.
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

An Evaluability Assessment of a School-Based Prevention Program: Promoting Evaluation Capacity Building. [PDF]

Justice Eval J
Krupa JM, Okyere AK, Parker JM.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Using legal capacity building to achieve Sustainable Development Goal 3.4: a global case study. [PDF]

Health Promot Int
Slattery C, Malone A, Zhou S, Jones H.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Perceptions and characteristics of the mentor role in research capacity building programs for clinicians: a scoping review and thematic analysis. [PDF]

BMC Med Educ
Flenady T, Calleja P, Sahay A, Wirihana L, Byrne AL.   +4 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source