Results 101 to 110 of about 219,591 (309)

A note on the capacity estimate in metastability for generic configurations

open access: yesmanuscripta mathematica
AbstractIn this paper we further develop the ideas from Geometric Function Theory initially introduced in Avelin et al. (Commun Math Phys 404:401–437, 2023), to derive capacity estimate in metastability for arbitrary configurations. The novelty of this paper is twofold.
Benny Avelin, Vesa Julin
openaire   +4 more sources

As a black start the wind power storage system has a storage capacity configuration

open access: yes, 2021
Through multiple simulations and statistics of its capacity deficit data, the basic value of the energy storage capacity that can cover most wind conditions is determined.
Yan Yan, Hu Haiming
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Performance Investigation of PEDF System Applied in Rural Areas

open access: yesZhongguo dianli
Photovoltaics, energy storage, direct current, and flexibility (PEDF), a new building power distribution system, is an important way to "carbon peak and carbon neutralization".
Chaoliang WANG   +3 more
doaj   +1 more source

Private Capacity and Public Failure: Contours of Livestock Innovation Response Capacity in Kenya [PDF]

open access: yes
Globalization, urbanization and new market demands - together with ever-increasing quality and safety requirements - are putting significantly greater pressures on agrifood stakeholders in the world.
Hall, Andy   +3 more
core  

Towards Low-Voltage and High-Capacity Conversion-Based Oxide Anodes by Configuration Entropy Optimization

open access: yes, 2023
Towards Low-Voltage and High-Capacity Conversion-Based Oxide Anodes by Configuration Entropy ...
SK Bhargava (14470950)   +11 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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