Results 71 to 80 of about 3,612,381 (259)

Configuration Sharing Optimized Placement and Routing [PDF]

open access: yes, 2010
Reconfigurable systems have been shown to achieve very high computational performance. However, the overhead associated with reconfiguration of hardware remains a critical factor in overall system performance.
Cobb, Jonathan E.   +3 more
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

The Capacity Configuration of a Cascade Small Hydropower-Pumped Storage–Wind–PV Complementary System

open access: yesApplied Sciences
Distributed renewable energy sources with significant output fluctuations can negatively impact the power grid stability when it is connected to the power grid.
Bin Li   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Hybrid Optimal Configuration Strategy for Unit Capacity of Modular Gravity Energy Storage Plant

open access: yes, 2023
Modular gravity energy storage (M-GES) is a new and promising large-scale energy storage technology, which is one of the essential solutions for large-scale renewable energy consumption.
Han, Minxiao   +7 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Optimization method for island and reef hybrid power generation systems' power capacity based on adaptive ant colony algorithm

open access: yesZhongguo Jianchuan Yanjiu
Objectives Aiming to address the existing challenges in the power capacity configuration of island and reef hybrid power generation systems, this paper proposes an optimization method based on the adaptive ant colony algorithm (ACA).
Weibo LI   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Capacity building assistance (CBA) glossary [PDF]

open access: yes
The Capacity Building Assistance (CBA) Glossary has been developed by the Capacity Building Assistance Provider Network (CPN) in partnership with the Capacity Building Branch (CBB), in the Division of HIV/AIDS Prevention (DHAP) at the Centers for Disease

core  

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