Results 91 to 100 of about 2,268,216 (315)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The critical importance of early grade reading and assessment [PDF]
, 2014 Working paper education sector analytical and capacity development partnership contains information about the critical importance of early grade reading and assessment with sub-sections as the importance of early grade reading, the science of reading ...
Analytical and Capacity Development Partnership (ACDP), Analytical and Capacity Development Partnership (ACDP)
core
Evaluation of Dutch support to capacity development
, 2013 Support for capacity development accounts for about 25 per cent of all international donor assistance. Yet there have been few evaluations to assess the effectiveness of this support. This paper presents the findings and lessons of an evaluation on Dutch
de Lange, Piet
core +1 more source
Country Program Evaluation: Costa Rica (2006-2010) [PDF]
, 2010 The Bank\u27s country strategy with Costa Rica 2006-2010 correctly identified the country\u27s main development challenges in 2006 (the baseline used by the Bank to prepare the strategy): the difficulty of forging linkages between the most dynamic ...
Inter-American Development Bank
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
International Journal of Health Services Research and Policy, 2019 The study used the county institutional capacity assessment tool (CICAT) to assess the capacities of selected county health departments (CHDs) along the World Health Organization (WHO) health systems framework that is organized around the six building ...
Vincent R. OKUNGU
doaj +1 more source
The 2023 Annual Report by the Office of Evaluation and Oversight (OVE), Contributions from Evaluation toward Improving the Bank\u27s Development Effectiveness, highlights findings and lessons from the different evaluations and products conducted ...
Inter-American Development Bank
core +1 more source
NDC INVEST: Regional Action that Inspires the World
, 2020 NDC Invest is a platform of the Inter-American Development (IDB) that offers a one-stop shop of technical and financial services across the project cycle, from policy and markets to project design and finance mobilization.
Inter-American Development Bank
core +1 more source
Heavenly Jade of the Maya [PDF]
, 2012 On the occasion of the thirtheenth bak\u27tun in the Maya calendar, the IDB Cultural Center and Country Department for Belize, Central America, México, Panama, and the Dominican Republic have come together to present this exhibition, which displays a ...
Inter-American Development Bank
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source