Results 111 to 120 of about 2,268,216 (315)

Country Program Evaluation: Uruguay (1991-2004) [PDF]

open access: yes, 2005
This country program evaluation (RE-312) covers the period from 1991 to 2004. It is composed of five chapters that evaluate the outcomes of the Bank\u27s program in Uruguay for the period 1991-2004 from different standpoints.
Inter-American Development Bank
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

When Passionate Leadership Stimulates Enduring Change : A Transformational Capacity Development Anecdote from Uganda

open access: yes, 2005
This paper from the water sector in Uganda turns on its head conventional wisdom about capacity growth and how long it takes to effect enduring change. This example of a transformational process that was driven by
Murphy, Patrice, Matta, Nadim
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Aid for Trade Report 2017

open access: yes, 2017
Aid for Trade (AfT) seeks to support developing countries as they strengthen trade capacity and infrastructure. As the World Trade Organization’s main institutional counterpart for AfT in LAC, the Inter-American Development Bank (IDB) remains committed ...
Inter-American Development Bank
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Building Post-Crisis Capacity in the Solomon Islands

open access: yes, 2009
This capacity development brief summarizes the results of a multi-donor team review of four examples of post-crisis capacity development interventions in the Solomon Islands in 2005-08 whose performance was
Bailey, Laura
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Workers’ Exposure to Respirable Dust and Quartz in the Southern African Large, Medium, Small and Artisanal Small-Scale Mining Industry: An Exploratory Study

open access: yesSafety
Mining activities are characterised by a multiplicity of inherent occupational hazards. Exposure to mineral dust such as silica, asbestos, and coal dust is common in mining, leading to pneumoconiosis.
Norman Nkuzi Khoza   +5 more
doaj   +1 more source

Advancing nursing scholarship: the Mozambique model

open access: yesGlobal Health Action, 2017
Background: Despite the importance of Human Resources for Health for the development and functioning of health systems worldwide, many countries continue to be plagued by poor health systems and a lack of adequate health care. Health systems failures may
Judith C. Bruce   +4 more
doaj   +1 more source

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