Results 141 to 150 of about 2,268,216 (315)

The role of trust and networks in developing Nicaraguan farmers’ agribusiness capacities

open access: yesJournal of Agriculture and Rural Development in the Tropics and Subtropics, 2018
The main focus of most programmes in developing countries carried out by NGOs is to develop small-scale farmers’ capacities. One approach hereby is to use multi-stakeholder innovation systems, such as the ‘Nicaraguan Learning Alliance’ (NLA).
Dirk Hauke Landmann   +1 more
doaj  

Course on Peace Violence and Development, 10 March - 31 May 2008 : SDPI Training Workshop

open access: yes, 2008
The course aimed to provide young professionals from diverse backgrounds in Pakistan a better understanding of research processes, improved analytical skills, and discussion of the connections between peace, development and violence.
Centre for Capacity Building
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Capacity development for conservation

open access: yesOryx, 2022
Mark O'Connell, Marianne Carter
openaire   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Building Synergies in Capacity Development - Recommendations and Capacity Development Resource Kit

open access: yes, 2019
This Recommendation package from the Capacity Development for Agriculture Data WG comprises two documents, the Recommendations document and the Capacity Development Resource Kit. This Capacity Development Resource Kit presents both the training requirements as defined by the IGAD community and available resources from the aforementioned groups: The ...
Anand, Suchith   +2 more
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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