The role of trust and networks in developing Nicaraguan farmers’ agribusiness capacities
The main focus of most programmes in developing countries carried out by NGOs is to develop small-scale farmers’ capacities. One approach hereby is to use multi-stakeholder innovation systems, such as the ‘Nicaraguan Learning Alliance’ (NLA).
Dirk Hauke Landmann +1 more
doaj
Course on Peace Violence and Development, 10 March - 31 May 2008 : SDPI Training Workshop
The course aimed to provide young professionals from diverse backgrounds in Pakistan a better understanding of research processes, improved analytical skills, and discussion of the connections between peace, development and violence.
Centre for Capacity Building
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Capacity development for conservation
Mark O'Connell, Marianne Carter
openaire +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Features that hindered the capacity development of a national prostate cancer service. [PDF]
Ward AL, Cruickshank S, Forbat L.
europepmc +1 more source
Building Synergies in Capacity Development - Recommendations and Capacity Development Resource Kit
This Recommendation package from the Capacity Development for Agriculture Data WG comprises two documents, the Recommendations document and the Capacity Development Resource Kit. This Capacity Development Resource Kit presents both the training requirements as defined by the IGAD community and available resources from the aforementioned groups: The ...
Anand, Suchith +2 more
openaire +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Developing a compassionate community: a Canadian conceptual model for community capacity development. [PDF]
Kelley ML.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source

