Results 111 to 120 of about 6,779,466 (261)
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Wind energy resource assessment in complex terrain regions requires high-resolution data and multidimensional risk evaluation beyond conventional wind speed climatology. This study uses a 40-year (1979–2018) WRF dynamical downscaling dataset assimilating
Mukeran Awa +4 more
doaj +1 more source
Division of Global Public Health Capacity Development 2008 annual report [PDF]
Based in Atlanta, Georgia (U.S.A.), the Division of Global Public Health Capacity Development (DGPHCD) is part of the Coordinating Office for Global Health at the U .S . Centers for Disease Control and Prevention.
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
This study investigates how offshore wind farm layout geometry influences farm-level performance using a computationally efficient Jensen–Park wake model combined with directionally resolved Weibull wind-speed statistics.
Kenneth Bisgaard Christensen +1 more
doaj +1 more source
PAYMENT CAPACITY SENSITIVITY FACTORS [PDF]
The current study focuses on the sensitivity of the corporate payment capacity. Through the nature of the subject, the research is based on simulating variations of the forecasted cash-flows of the companies included in the sample. The study employs 391 forecasted yearly cash-flows statements collected from 50 companies from Timis County (Romania), as ...
openaire +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
One of the directions of development of the electric power industry is decentralization, aimed at improving the reliability of energy supply, reducing losses during transmission of electric energy and ensuring energy independence of consumers.
A. M. Bramm +3 more
doaj +1 more source
Alternations to shop at 357 Glenhuntly Rd., Elsternwick
Commercial; shop; alternations to existing premisesPhysical format : thick stock paper; 845x600mmIncludes plan and elevationsMichael Factor, architectScale: 1 ...
Factor, Michael
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

