Results 111 to 120 of about 6,779,466 (261)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Assessing Wind Power Potential, Multidimensional Wind Risk, and Development Suitability in Xinjiang, China, During 1979–2018

open access: yesAtmosphere
Wind energy resource assessment in complex terrain regions requires high-resolution data and multidimensional risk evaluation beyond conventional wind speed climatology. This study uses a 40-year (1979–2018) WRF dynamical downscaling dataset assimilating
Mukeran Awa   +4 more
doaj   +1 more source

Division of Global Public Health Capacity Development 2008 annual report [PDF]

open access: yes
Based in Atlanta, Georgia (U.S.A.), the Division of Global Public Health Capacity Development (DGPHCD) is part of the Coordinating Office for Global Health at the U .S . Centers for Disease Control and Prevention.

core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Parametric Analysis of Offshore Wind Farm Layout Geometry Using a Jensen Wake Model for 15 MW Turbine Systems

open access: yesWind
This study investigates how offshore wind farm layout geometry influences farm-level performance using a computationally efficient Jensen–Park wake model combined with directionally resolved Weibull wind-speed statistics.
Kenneth Bisgaard Christensen   +1 more
doaj   +1 more source

PAYMENT CAPACITY SENSITIVITY FACTORS [PDF]

open access: yesManagement Intercultural, 2014
The current study focuses on the sensitivity of the corporate payment capacity. Through the nature of the subject, the research is based on simulating variations of the forecasted cash-flows of the companies included in the sample. The study employs 391 forecasted yearly cash-flows statements collected from 50 companies from Timis County (Romania), as ...
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Capacity Factor Forecasting for Generation Facilities Based on Renewable Energy Sources in Decentralized Power Systems

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика
One of the directions of development of the electric power industry is decentralization, aimed at improving the reliability of energy supply, reducing losses during transmission of electric energy and ensuring energy independence of consumers.
A. M. Bramm   +3 more
doaj   +1 more source

Alternations to shop at 357 Glenhuntly Rd., Elsternwick

open access: yes, 1989
Commercial; shop; alternations to existing premisesPhysical format : thick stock paper; 845x600mmIncludes plan and elevationsMichael Factor, architectScale: 1 ...
Factor, Michael
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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