Results 31 to 40 of about 307,350 (217)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A Microgrid Source-Storage Optimization Method Considering Full-Cycle Chronological Order Characteristics

open access: yesShanghai Jiaotong Daxue xuebao
To meet the requirements of large capacity energy storage optimal design, particulaly regarding optimization, a microgrid source-storage optimization method considering full-cycle chronological order characteristics is proposed.
WANG Xiaobo, JIA Yongyong, LI Zheng, LI Wenbo, JIA Yuqiao, LI Huarui, ZHU Xinyao
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Capacity Optimization Method for Photovoltaic Hydrogen Production Systems Based on Multi-Objective Particle Swarm Algorithm

open access: yes南方能源建设
[Objective] The hydrogen production system utilizes solar energy to convert water into hydrogen, aiming to reduce carbon emissions and improve the efficiency of renewable energy utilization.
Haotian LU, Shaopeng LIU, Kai WANG
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Mixed Production Line Optimization of Industrialized Building Based on Ant Colony Optimization Algorithm

open access: yesAdvances in Civil Engineering, 2022
Prefabricated components production line optimization is critical for improving industrialized building construction efficiency; however, few studies focus on the production line optimization problem in context of industrialized building construction. In
Xiaobo Chen   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Asymmetric Loss Functions for Contract Capacity Optimization

open access: yesEnergies, 2020
For high-voltage and extra-high-voltage consumers, the electricity cost depends not only on the power consumed but also on the contract capacity. For the same amount of power consumed, the smaller the difference between the contract capacity and the ...
Jun-Lin Lin   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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